Target Gene/Pathway Pathway / Gene


Search results


No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 PDE10A [4] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction D00371 Theophylline [2] 236, 299
2 PDE10A [4] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction D01712 Theophylline [2] 236, 299
3 PDE10A [4] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction D02017 Theophylline [2] 236, 299
4 PDE10A [4] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction D06103 Theophylline [2] 236, 299
5 PDE10A [4] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction D06104 Theophylline [2] 236, 299
6 ADORA1 [7] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D00371 Theophylline [2] 236, 299
7 ADORA1 [7] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D01712 Theophylline [2] 236, 299
8 ADORA1 [7] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D02017 Theophylline [2] 236, 299
9 ADORA1 [7] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D06103 Theophylline [2] 236, 299
10 ADORA1 [7] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D06104 Theophylline [2] 236, 299
11 ADORA2A [7] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Parkinson disease, Alcoholism D02017 Theophylline [2] 236, 299
12 ADORA2B [5] Rap1 signaling pathway, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Alcoholism D00371 Theophylline [2] 236, 299
13 ADORA2B [5] Rap1 signaling pathway, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Alcoholism D01712 Theophylline [2] 236, 299
14 ADORA2B [5] Rap1 signaling pathway, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Alcoholism D06103 Theophylline [2] 236, 299
15 ADORA2B [5] Rap1 signaling pathway, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Alcoholism D06104 Theophylline [2] 236, 299
16 GHR [5] Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Growth hormone synthesis, secretion and action D02691 Somatotropin [23] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
17 PDE7B [3] Purine metabolism, Metabolic pathways, Morphine addiction D00371 Theophylline [2] 236, 299
18 PDE7B [3] Purine metabolism, Metabolic pathways, Morphine addiction D01712 Theophylline [2] 236, 299
19 PDE7B [3] Purine metabolism, Metabolic pathways, Morphine addiction D02017 Theophylline [2] 236, 299
20 PDE7B [3] Purine metabolism, Metabolic pathways, Morphine addiction D06103 Theophylline [2] 236, 299
21 PDE7B [3] Purine metabolism, Metabolic pathways, Morphine addiction D06104 Theophylline [2] 236, 299
22 PDE11A [4] Purine metabolism, Metabolic pathways, Cushing syndrome, Morphine addiction D00371 Theophylline [2] 236, 299
23 PDE11A [4] Purine metabolism, Metabolic pathways, Cushing syndrome, Morphine addiction D01712 Theophylline [2] 236, 299
24 PDE11A [4] Purine metabolism, Metabolic pathways, Cushing syndrome, Morphine addiction D02017 Theophylline [2] 236, 299
25 PDE11A [4] Purine metabolism, Metabolic pathways, Cushing syndrome, Morphine addiction D06103 Theophylline [2] 236, 299
26 PDE11A [4] Purine metabolism, Metabolic pathways, Cushing syndrome, Morphine addiction D06104 Theophylline [2] 236, 299
27 PDE1A [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D00371 Theophylline [2] 236, 299
28 PDE1A [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D01712 Theophylline [2] 236, 299
29 PDE1A [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D02017 Theophylline [2] 236, 299
30 PDE1A [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D06103 Theophylline [2] 236, 299
31 PDE1A [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D06104 Theophylline [2] 236, 299
32 PDE1C [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D00371 Theophylline [2] 236, 299
33 PDE1C [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D01712 Theophylline [2] 236, 299
34 PDE1C [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D02017 Theophylline [2] 236, 299
35 PDE1C [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D06103 Theophylline [2] 236, 299
36 PDE1C [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D06104 Theophylline [2] 236, 299
37 PDE2A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction D00371 Theophylline [2] 236, 299
38 PDE2A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction D01712 Theophylline [2] 236, 299
39 PDE2A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction D02017 Theophylline [2] 236, 299
40 PDE2A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction D06103 Theophylline [2] 236, 299
41 PDE2A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction D06104 Theophylline [2] 236, 299
42 PDE3A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction D00371 Theophylline [2] 236, 299
43 PDE3A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction D01712 Theophylline [2] 236, 299
44 PDE3A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction D02017 Theophylline [2] 236, 299
45 PDE3A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction D06103 Theophylline [2] 236, 299
46 PDE3A [6] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction D06104 Theophylline [2] 236, 299
47 PDE3B [11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D00371 Theophylline [2] 236, 299
48 PDE3B [11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D01712 Theophylline [2] 236, 299
49 PDE3B [11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D02017 Theophylline [2] 236, 299
50 PDE3B [11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D06103 Theophylline [2] 236, 299
51 PDE3B [11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D06104 Theophylline [2] 236, 299
52 PDE4A [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D00371 Theophylline [2] 236, 299
53 PDE4A [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D01712 Theophylline [2] 236, 299
54 PDE4A [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D02017 Theophylline [2] 236, 299
55 PDE4A [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06103 Theophylline [2] 236, 299
56 PDE4A [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06104 Theophylline [2] 236, 299
57 PDE4B [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D00371 Theophylline [2] 236, 299
58 PDE4B [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D01712 Theophylline [2] 236, 299
59 PDE4B [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D02017 Theophylline [2] 236, 299
60 PDE4B [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06103 Theophylline [2] 236, 299
61 PDE4B [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06104 Theophylline [2] 236, 299
62 PDE4C [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D00371 Theophylline [2] 236, 299
63 PDE4C [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D01712 Theophylline [2] 236, 299
64 PDE4C [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D02017 Theophylline [2] 236, 299
65 PDE4C [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06103 Theophylline [2] 236, 299
66 PDE4C [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06104 Theophylline [2] 236, 299
67 PDE4D [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D00371 Theophylline [2] 236, 299
68 PDE4D [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D01712 Theophylline [2] 236, 299
69 PDE4D [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D02017 Theophylline [2] 236, 299
70 PDE4D [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06103 Theophylline [2] 236, 299
71 PDE4D [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction D06104 Theophylline [2] 236, 299
72 PDE7A [3] Purine metabolism, Metabolic pathways, Morphine addiction D00371 Theophylline [2] 236, 299
73 PDE7A [3] Purine metabolism, Metabolic pathways, Morphine addiction D01712 Theophylline [2] 236, 299
74 PDE7A [3] Purine metabolism, Metabolic pathways, Morphine addiction D02017 Theophylline [2] 236, 299
75 PDE7A [3] Purine metabolism, Metabolic pathways, Morphine addiction D06103 Theophylline [2] 236, 299
76 PDE7A [3] Purine metabolism, Metabolic pathways, Morphine addiction D06104 Theophylline [2] 236, 299
77 PDE8A [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D00371 Theophylline [2] 236, 299
78 PDE8A [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D01712 Theophylline [2] 236, 299
79 PDE8A [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D02017 Theophylline [2] 236, 299
80 PDE8A [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D06103 Theophylline [2] 236, 299
81 PDE8A [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D06104 Theophylline [2] 236, 299
82 PDE1B [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D00371 Theophylline [2] 236, 299
83 PDE1B [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D01712 Theophylline [2] 236, 299
84 PDE1B [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D02017 Theophylline [2] 236, 299
85 PDE1B [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D06103 Theophylline [2] 236, 299
86 PDE1B [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction D06104 Theophylline [2] 236, 299
87 PDE8B [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D00371 Theophylline [2] 236, 299
88 PDE8B [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D01712 Theophylline [2] 236, 299
89 PDE8B [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D02017 Theophylline [2] 236, 299
90 PDE8B [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D06103 Theophylline [2] 236, 299
91 PDE8B [5] Purine metabolism, Metabolic pathways, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction D06104 Theophylline [2] 236, 299