Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CPT1C [1] Thermogenesis D05442 Perhexiline [2] 58, 272
2 CPT1C [1] Thermogenesis D08340 Perhexiline [2] 58, 272
3 CNR1 [1] Thermogenesis D00306 Dronabinol [8] 2, 8, 13, 36, 46, 96, 271, 298
4 CNR1 [1] Thermogenesis D05099 Nabilone [2] 6, 13
5 CNR1 [1] Thermogenesis D05731 Rimonabant [1] 193
6 CNR1 [1] Thermogenesis D10915 Cannabidiol [19] 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
7 CPT1A [1] Thermogenesis D05442 Perhexiline [2] 58, 272
8 CPT1A [1] Thermogenesis D08340 Perhexiline [2] 58, 272
9 CPT1B [1] Thermogenesis D05442 Perhexiline [2] 58, 272
10 CPT1B [1] Thermogenesis D08340 Perhexiline [2] 58, 272
11 CPT2 [1] Thermogenesis D05442 Perhexiline [2] 58, 272
12 CPT2 [1] Thermogenesis D08340 Perhexiline [2] 58, 272
13 MAPK14 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
14 MAPK14 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
15 ADRB3 [1] Thermogenesis D00076 Norepinephrine [1] 22
16 ADRB3 [1] Thermogenesis D00095 Epinephrine [3] 46, 70, 96
17 ADRB3 [1] Thermogenesis D00124 Ephedrine [1] 11
18 ADRB3 [1] Thermogenesis D00483 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
19 ADRB3 [1] Thermogenesis D00485 Pseudoephedrine [1] 17
20 ADRB3 [1] Thermogenesis D00996 Epinephrine [3] 46, 70, 96
21 ADRB3 [1] Thermogenesis D01277 Droxidopa [5] 5, 6, 17, 169, 170
22 ADRB3 [1] Thermogenesis D02149 Epinephrine [3] 46, 70, 96
23 ADRB3 [1] Thermogenesis D02349 Dipivefrin [1] 6
24 ADRB3 [1] Thermogenesis D05206 Norepinephrine [1] 22
25 ADRB3 [1] Thermogenesis D05648 Pseudoephedrine [1] 17
26 ADRB3 [1] Thermogenesis D05649 Pseudoephedrine [1] 17
27 ADRB3 [1] Thermogenesis D08443 Propranolol [7] 6, 158, 167, 215, 227, 278, 296
28 ADRB3 [1] Thermogenesis D08449 Pseudoephedrine [1] 17
29 ADRB3 [1] Thermogenesis D09535 Mirabegron [4] 6, 13, 53, 226
30 FGFR1 [1] Thermogenesis D10481 Nintedanib [5] 51, 85, 89, 227, 228
31 FGFR1 [1] Thermogenesis D11589 Infigratinib [1] 276
32 MTOR [3] Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus D00753 Sirolimus [41] 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
33 MTOR [3] Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
34 MTOR [3] Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus D06068 Temsirolimus [4] 13, 34, 89, 331
35 MAP3K5 [3] Tight junction, TNF signaling pathway, Thermogenesis D10988 Selonsertib [1] 86
36 NPR1 [2] Vascular smooth muscle contraction, Thermogenesis D04051 Erythrityl tetranitrate [1] 46
37 NPR1 [2] Vascular smooth muscle contraction, Thermogenesis D05147 Nesiritide [2] 46, 58
38 PPARG [3] Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D00596 Rosiglitazone [5] 46, 75, 97, 222, 265
39 PPARG [3] Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D00945 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
40 PPARG [3] Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D08378 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
41 PPARG [3] Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D08491 Rosiglitazone [5] 46, 75, 97, 222, 265
42 PPARG [3] Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D11256 Seladelpar [2] 93, 94
43 PPARG [3] Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D11603 Leriglitazone [1] 20
44 PRKAA1 [2] Tight junction, Thermogenesis D00944 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
45 PRKAA1 [2] Tight junction, Thermogenesis D04966 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
46 PRKAA2 [2] Tight junction, Thermogenesis D00944 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
47 PRKAA2 [2] Tight junction, Thermogenesis D04966 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
48 MAPK11 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
49 MAPK11 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
50 MAPK13 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
51 MAPK13 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
52 MAPK12 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
53 MAPK12 [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8