Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Thermogenesis 💬
 [1] ADRB3 💬 D02349 💬 Dipivefrin [1]  6  💬
2 Thermogenesis 💬
 [1] ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
3 Thermogenesis 💬
 [1] ADRB3 💬 D00124 💬 Ephedrine [1] 11 💬
4 Thermogenesis 💬
 [1] ADRB3 💬 D00095 💬 Epinephrine [3] 46, 70, 96 💬
5 Thermogenesis 💬
 [1] ADRB3 💬 D00996 💬 Epinephrine [3] 46, 70, 96 💬
6 Thermogenesis 💬
 [1] ADRB3 💬 D02149 💬 Epinephrine [3] 46, 70, 96 💬
7 Thermogenesis 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
8 Thermogenesis 💬
 [1] ADRB3 💬 D00076 💬 Norepinephrine [1] 22 💬
9 Thermogenesis 💬
 [1] ADRB3 💬 D05206 💬 Norepinephrine [1] 22 💬
10 Thermogenesis 💬
 [1] ADRB3 💬 D00483 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
11 Thermogenesis 💬
 [1] ADRB3 💬 D08443 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
12 Thermogenesis 💬
 [1] ADRB3 💬 D00485 💬 Pseudoephedrine [1] 17 💬
13 Thermogenesis 💬
 [1] ADRB3 💬 D05648 💬 Pseudoephedrine [1] 17 💬
14 Thermogenesis 💬
 [1] ADRB3 💬 D05649 💬 Pseudoephedrine [1] 17 💬
15 Thermogenesis 💬
 [1] ADRB3 💬 D08449 💬 Pseudoephedrine [1] 17 💬
16 Thermogenesis 💬
 [1] CNR1 💬 D10915 💬 Cannabidiol [19]  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
17 Thermogenesis 💬
 [1] CNR1 💬 D00306 💬 Dronabinol [8]  2 ,  8 , 13, 36, 46, 96, 271, 298 💬
18 Thermogenesis 💬
 [1] CNR1 💬 D05099 💬 Nabilone [2]  6 , 13 💬
19 Thermogenesis 💬
 [1] CNR1 💬 D05731 💬 Rimonabant [1] 193 💬
20 Thermogenesis 💬
 [4] CPT1A, CPT1B, CPT1C, CPT2 💬 D05442 💬 Perhexiline [2] 58, 272 💬
21 Thermogenesis 💬
 [4] CPT1A, CPT1B, CPT1C, CPT2 💬 D08340 💬 Perhexiline [2] 58, 272 💬
22 Thermogenesis 💬
 [1] FGFR1 💬 D11589 💬 Infigratinib [1] 276 💬
23 Thermogenesis 💬
 [1] FGFR1 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
24 Thermogenesis 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
25 Thermogenesis 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
26 Thermogenesis 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
27 Thermogenesis 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
28 Thermogenesis 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
29 Thermogenesis 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
30 Thermogenesis 💬
 [1] NPR1 💬 D04051 💬 Erythrityl tetranitrate [1] 46 💬
31 Thermogenesis 💬
 [1] NPR1 💬 D05147 💬 Nesiritide [2] 46, 58 💬
32 Thermogenesis 💬
 [1] PPARG 💬 D11603 💬 Leriglitazone [1] 20 💬
33 Thermogenesis 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
34 Thermogenesis 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
35 Thermogenesis 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
36 Thermogenesis 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
37 Thermogenesis 💬
 [1] PPARG 💬 D11256 💬 Seladelpar [2] 93, 94 💬
38 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
39 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬