Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Toxoplasmosis 💬
[1] ALOX5 💬 D01773 💬 Oxatomide [1] 113 💬
2 Toxoplasmosis 💬
[1] ALOX5 💬 D00414 💬 Zileuton [3] 85, 160, 164 💬
3 Toxoplasmosis 💬
[1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
4 Toxoplasmosis 💬
[1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
5 Toxoplasmosis 💬
[1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
6 Toxoplasmosis 💬
[1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
7 Toxoplasmosis 💬
[1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
8 Toxoplasmosis 💬
[1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
9 Toxoplasmosis 💬
[1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
10 Toxoplasmosis 💬
[1] CD40LG 💬 D06193 💬 Toralizumab [1] 63 💬
11 Toxoplasmosis 💬
[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 D04318 💬 Glatiramer [4]  2 , 13, 96, 156 💬
12 Toxoplasmosis 💬
[1] IFNG 💬 D11120 💬 Emapalumab [2] 49, 107 💬
13 Toxoplasmosis 💬
[1] IFNG 💬 D04242 💬 Fontolizumab [1] 46 💬
14 Toxoplasmosis 💬
[2] IFNGR1, IFNGR2 💬 D00747 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
15 Toxoplasmosis 💬
[2] IL10, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
16 Toxoplasmosis 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
17 Toxoplasmosis 💬
[1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
18 Toxoplasmosis 💬
[1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
19 Toxoplasmosis 💬
[1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
20 Toxoplasmosis 💬
[2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
21 Toxoplasmosis 💬
[2] JAK1, JAK2 💬 D10653 💬 Peficitinib [1] 46 💬
22 Toxoplasmosis 💬
[2] JAK1, JAK2 💬 D09959 💬 Ruxolitinib [1] 228 💬
23 Toxoplasmosis 💬
[3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
24 Toxoplasmosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
25 Toxoplasmosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
26 Toxoplasmosis 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
27 Toxoplasmosis 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
28 Toxoplasmosis 💬
[3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬
29 Toxoplasmosis 💬
[1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
30 Toxoplasmosis 💬
[1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
31 Toxoplasmosis 💬
[1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
32 Toxoplasmosis 💬
[1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
33 Toxoplasmosis 💬
[1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
34 Toxoplasmosis 💬
[1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
35 Toxoplasmosis 💬
[1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
36 Toxoplasmosis 💬
[1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
37 Toxoplasmosis 💬
[1] TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
38 Toxoplasmosis 💬
[1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
39 Toxoplasmosis 💬
[1] TYK2 💬 D11817 💬 Deucravacitinib [2] 96, 97 💬