Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Avacincaptad pegol [1] Avacincaptad pegol---[1] 301 💬
2 Doconexent [2] Docosahexaenoic acid; Docosahexanoic Acid---[10] 6, 46, 48, 49, 90, 94, 113, 240, 299, 301 💬
3 Emixustat [1] Emixustat[1] Emixustat 💬--[1] 301 💬
4 Fomepizole [1] 4-Methylpyrazole[1] Fomepizole 💬[3] ADH1A,
ADH1B,
ADH1C 💬		[9] Alcoholic liver disease, Drug metabolism - cytochrome P450, Fatty acid degradation, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pyruvate metabolism, Retinol metabolism, Tyrosine metabolism 💬[1] 301 💬
5 Icosapent [2] Eicosapentaenoic Acid; Icosapent[1] Icosapent 💬--[11] 8, 46, 48, 49, 96, 97, 113, 296, 297, 301, 338 💬
6 Interferon Gamma [1] Interferon Gamma---[8] 18, 65, 85, 107, 228, 299, 301, 326 💬
7 Interferon gamma-1b [2] ACTIMMUNE; Interferon gamma-1b[1] Interferon gamma-1b 💬[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
8 Metformin [5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[1] Metformin 💬[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
9 Ranibizumab [3] Lucentis; RANIBIZUMAB; RhuFab V2[1] Ranibizumab 💬[1] VEGFA 💬[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[4] 34, 166, 227, 301 💬
10 Sildenafil [6] Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; VIAGRA[1] Sildenafil 💬[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
11 STG-001 [1] STG-001---[1] 301 💬