Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 L-Acetylleucine [2] Acetyl-l-leucine; N-Acetyl-L-Leucine---[2] 19, 65 💬
2 L-arginine [1] L-Arginine[1] Arginine 💬--[8] 46, 67, 78, 96, 97, 98, 113, 299 💬
3 L-Glutamine [2] Glutamine; L-Glutamine[1] Glutamine 💬--[8] 87, 89, 96, 97, 113, 222, 245, 299 💬
4 Lacosamide [1] Lacosamide[1] Lacosamide 💬[2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[4] 2, 46, 149, 298 💬
5 Lactic acid [1] Lactic acid[1] Lactic acid 💬--[1] 299 💬
6 Lactobacillus acidophilus [4] Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus[1] Lactomin 💬--[3] 6, 49, 97 💬
7 Lactobacillus casei [2] Fusion; Lactobacillus casei[1] Lactobacillus casei 💬--[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296 💬
8 Lactobacillus delbrueckii bulgaricus [1] Lactobacillus---[5] 6, 46, 51, 97, 299 💬
9 Lactobacillus plantarum [1] Lactobacillus plantarum---[3] 6, 97, 156 💬
10 Lactobacillus reuteri [1] LACTOBACILLUS REUTERI---[2] 97, 299 💬
11 Lactobacillus salivarius [1] Lactobacillus salivarius---[2] 96, 97 💬
12 Lactose [1] Lactose[2] Anhydrous lactose ,
Lactose 💬		--[6] 2, 6, 13, 97, 228, 310 💬
13 Lactulose [1] Lactulose[1] Lactulose 💬--[3] 13, 96, 291 💬
14 Ladarixin [1] Ladarixin---[1] 162 💬
15 Lamivudine [4] COMBIVIR; Epivir; Lamivudine; Triumeq[1] Lamivudine 💬--[8] 2, 26, 42, 46, 135, 256, 265, 325 💬
16 Lamotrigine [2] Lamictal; Lamotrigine[1] Lamotrigine 💬[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 13, 34, 38, 114, 144 💬
17 Lancovutide [1] DURAMYCIN---[1] 299 💬
18 Lanifibranor [1] LANIFIBRANOR---[1] 51 💬
19 Lanraplenib [1] Lanraplenib[1] Lanraplenib 💬--[2] 53, 222 💬
20 Lanreotide [3] Lanreotide; LANREOTIDE ACETATE; Somatuline Autogel---[4] 67, 73, 85, 298 💬
21 Lansoprazole [1] Lansoprazole[1] Lansoprazole 💬[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299 💬
22 Lapaquistat [1] Lapaquistat---[1] 79 💬
23 Lapatinib [1] Lapatinib[1] Lapatinib 💬[2] EGFR,
ERBB2 💬		[50] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬[3] 34, 74, 75 💬
24 Laquinimod [1] LAQUINIMOD---[4] 8, 13, 49, 96 💬
25 Laronidase [2] Aldurazyme; Laronidase[1] Laronidase 💬[1] IDUA 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[2] 19, 256 💬
26 Latozinemab [2] AL001; Latozinemab[1] Latozinemab 💬[1] SORT1 💬[3] Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬[2] 2, 127 💬
27 Latrepirdine [2] Dimebon; Latrepirdine[1] Latrepirdine 💬[6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8 💬
28 LAX-101 [1] LAX-101---[1] 8 💬
29 Lebrikizumab [1] LEBRIKIZUMAB[1] Lebrikizumab 💬[1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 85 💬
30 Lecithin [1] Phosphatidylcholine[1] Lecithin 💬--[1] 97 💬
31 Ledipasvir [1] Ledipasvir[1] Ledipasvir 💬--[1] 19 💬
32 Lefamulin [1] Lefamulin[1] Lefamulin 💬--[1] 299 💬
33 Leflunomide [3] Arava; LEFLUNOMIDE; Leflunomidum[1] Leflunomide 💬[1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
34 Lenadogene nolparvovec [1] Lenadogene nolparvovec---[1] 302 💬
35 Lenalidomide [2] Lenalidomide; REVLIMID[1] Lenalidomide 💬[1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
36 Leniolisib [1] Leniolisib[1] Leniolisib 💬[3] PIK3CA,
PIK3CB,
PIK3CD 💬		[106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[2] 53, 65 💬
37 Lenograstim [2] G-CSF; Lenograstim[1] Lenograstim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65 💬
38 Lenomorelin [1] Ghrelin---[6] 6, 78, 193, 201, 202, 299 💬
39 Lenzumestrocel [1] Lenzumestrocel---[1] 2 💬
40 Leptin [1] Leptin---[2] 6, 265 💬
41 Leriglitazone [1] Leriglitazone[1] Leriglitazone 💬[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 20 💬
42 Letermovir [1] Letermovir[1] Letermovir 💬--[1] 85 💬
43 Letrozole [1] Letrozole[1] Letrozole 💬[1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[2] 81, 89 💬
44 Leucine [2] L-leucine; Leucine[1] Leucine 💬--[6] 6, 19, 65, 283, 284, 299 💬
45 Leucovorin [2] Folinic acid; Leucovorin[2] Folinic acid ,
Folinic acid calcium salt pentahydrate 💬		--[4] 19, 46, 107, 320 💬
46 Leuprolide [3] Leuprolide; Leuprolide acetate depot; Leuprorelin---[6] 1, 2, 3, 51, 67, 76 💬
47 Levamisole [1] Levamisole[1] Levamisole 💬--[4] 60, 61, 62, 222 💬
48 Levetiracetam [2] KEPPRA; Levetiracetam[1] Levetiracetam 💬[1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
49 Levobupivacaine [2] Bupivacaine; Levobupivacaine[1] Levobupivacaine 💬[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 46 💬
50 Levocarnitine [4] Carnitine; L-Carnitine; Levocarnitine; Xyzal[1] Levocarnitine 💬--[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
51 Levocarnitine propionate [1] Propionyl-L-Carnitine---[1] 97 💬
52 Levocetirizine [1] Levocetirizina[1] Levocetirizine 💬[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 61 💬
53 Levodopa [9] Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] Levodopa 💬[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[6] 6, 17, 90, 140, 164, 201 💬
54 Levofloxacin [2] Levaquin; Levofloxacin[2] Levofloxacin ,
Levofloxacin 💬		--[5] 46, 53, 84, 85, 299 💬
55 Levoketoconazole [1] Levoketoconazole[1] Levoketoconazole 💬[3] CYP11A1,
CYP11B1,
CYP17A1 💬		[7] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[1] 75 💬
56 Levoleucovorin [1] Levofolene---[1] 13 💬
57 Levomefolic acid [1] L-methylfolate[1] Levomefolic acid 💬--[2] 6, 201 💬
58 Levonorgestrel [1] LEVONORGESTREL[1] Levonorgestrel 💬[1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
59 Levosalbutamol [2] R-salbutamol; Salbutamol[1] Levosalbutamol 💬[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 49 💬
60 Levosimendan [1] LEVOSIMENDAN[1] Levosimendan 💬[2] PDE3A,
PDE3B 💬		[11] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2 💬
61 Levothyroxine [2] Levothyroxine; Thyroxine[1] Levothyroxine 💬[2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[5] 19, 49, 78, 80, 222 💬
62 Liatermin [2] Liatermin; R-metHuGDNF[1] Liatermin 💬--[1] 6 💬
63 Licorice [2] Licorice; Liquorice[1] Glycyrrhiza 💬--[2] 53, 83 💬
64 Lidocaine [4] Aloe; Lidocaine; Lignocaine; Xylocaine[2] Lidocaine ,
Lidocaine hydrochloride monohydrate 💬		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
65 Limaprost [1] Limaprost[1] Limaprost 💬[1] PTGER1 💬[4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬[1] 70 💬
66 Linaclotide [1] Linaclotide[1] Linaclotide 💬[1] GUCY2C 💬[2] Metabolic pathways, Purine metabolism 💬[2] 6, 97 💬
67 Linezolid [1] LINEZOLID[1] Linezolid 💬--[1] 299 💬
68 Linoleic acid [1] Linoleic acid---[8] 2, 5, 6, 13, 76, 78, 256, 299 💬
69 Linperlisib [1] Linperlisib---[1] 61 💬
70 Linsitinib [1] Linsitinib[1] Linsitinib 💬[1] IGF1R 💬[29] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, HIF-1 signaling pathway, Hepatocellular carcinoma, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[1] 232 💬
71 Liothyronine [3] Liothyronine; Liothyronine sodium; Triiodothyronine[1] Liothyronine 💬[2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 13, 78, 210, 212 💬
72 Liothyronine I-131 [1] Liothyronine I 131---[2] 210, 212 💬
73 Lipoic acid [3] Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid---[5] 2, 5, 13, 14, 20 💬
74 Liraglutide [2] LIRAGLUTIDE; Saxenda[1] Liraglutide 💬[1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 6, 75, 193 💬
75 Lirentelimab [1] Lirentelimab[1] Lirentelimab 💬[1] SIGLEC8 💬-[1] 98 💬
76 Lisdexamfetamine [1] Lisdexamfetamine[1] Lisdexamfetamine 💬[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13 💬
77 Lisinopril [2] Lisinopril; ZESTRIL[2] Lisinopril ,
Lisinopril 💬		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222 💬
78 Lisuride [1] Lisuride[1] Lisuride 💬[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86 💬
79 Lithium carbonate [2] Lithium; Lithium Carbonate[1] Lithium carbonate 💬--[5] 2, 13, 17, 18, 127 💬
80 Lithium citrate [2] Lithium; LITHIUM CITRATE[1] Lithium citrate 💬--[5] 2, 5, 6, 7, 8 💬
81 Livoletide [1] Livoletide---[1] 193 💬
82 Lixisenatide [1] Lixisenatide[1] Lixisenatide 💬[1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
83 Lixivaptan [1] Lixivaptan[1] Lixivaptan 💬[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67 💬
84 Lomerizine [1] Lomerizine---[1] 124 💬
85 Lomitapide [2] Lojuxta; LOMITAPIDE[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
86 Lonafarnib [1] Lonafarnib[1] Lonafarnib 💬[2] FNTA,
FNTB 💬		[1] Terpenoid backbone biosynthesis 💬[2] 113, 333 💬
87 Lonapegsomatropin [1] LONAPEGSOMATROPIN[1] Lonapegsomatropin 💬[1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78 💬
88 Loperamide [2] LOPERAMIDE; Loperamide hydrochloride[1] Loperamide 💬[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97 💬
89 Lopinavir [2] Kaletra; Lopinavir[1] Lopinavir 💬--[2] 93, 265 💬
90 Loratadine [2] Loratadina; Loratadine[1] Loratadine 💬[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98 💬
91 Lorazepam [1] Lorazepam[1] Lorazepam 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 36 💬
92 Lorcaserin [1] Lorcaserin---[1] 140 💬
93 Losartan [3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] Losartan 💬[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
94 Losmapimod [1] LOSMAPIMOD[1] Losmapimod 💬[4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬		[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[2] 113, 222 💬
95 Lovastatin [1] Lovastatin[1] Lovastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
96 Loxoprofen [1] Loxoprofen[1] Loxoprofen 💬[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 46, 271 💬
97 Lubiprostone [1] LUBIPROSTONE[1] Lubiprostone 💬[1] CLCN2 💬[1] Mineral absorption 💬[4] 6, 13, 290, 299 💬
98 Lucerastat [1] Lucerastat[1] Lucerastat 💬[1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19 💬
99 Lucinactant [1] Lucinactant[1] Lucinactant 💬--[1] 299 💬
100 Lulizumab pegol [2] BMS-931699; Lulizumab Pegol---[3] 49, 53, 160 💬
101 Lumacaftor [2] LUMACAFTOR; Orkambi[1] Lumacaftor 💬[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
102 Lumasiran [1] LUMASIRAN[1] Lumasiran 💬[1] HAO1 💬[4] Carbon metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Peroxisome 💬[1] 234 💬
103 Lumiracoxib [1] Lumiracoxib[1] Lumiracoxib 💬[1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46 💬
104 Lunasine [1] Lunasin---[1] 2 💬
105 Luspatercept [1] Luspatercept[1] Luspatercept 💬[1] ACVR2B 💬[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 60 💬
106 Lutein [1] Lutein---[3] 13, 90, 164 💬
107 Luteinizing hormone [1] Luteinizing hormone---[1] 254 💬
108 LY3884961 [1] LY3884961---[1] 19 💬
109 Lysine [1] Lysine[1] Lysine 💬--[5] 13, 19, 97, 228, 299 💬