Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Chenodiol 💬 [1] Chenodeoxycholic acid[3] CDCA; Chenodeoxycholic acid; Chenodiol; [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 96, 234, 263 💬
2 Cyclosporine 💬 [1] Cyclosporine[10] CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; Restasis; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
3 Melphalan 💬 [1] Melphalan[3] Alkeran; Melphalan; Melphalan Hydrochloride; --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
4 Ursodiol 💬 [1] Ursodeoxycholic acid[4] UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk; [1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
5 Mycophenolate mofetil 💬 [1] Mycophenolate mofetil[3] CELLCEPT; Mycophenolate mofetil; Mycophenolate mofetil TEVA; [2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
6 Alemtuzumab 💬 [1] Alemtuzumab[4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH; [1] CD52 💬[1] 💬[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
7 Clofarabine 💬 [1] Clofarabine[1] Clofarabine; [3] POLA1,
POLA2,
RRM1 💬		[7] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 234, 326 💬
8 Mycophenolic acid 💬 [1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic; [2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
9 Hydroxychloroquine 💬 [1] Hydroxychloroquine[3] Hydroxychloroquine; Hydroxychloroquine sulfate; Plaquenil; --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
10 Cholic acid 💬 [1] Cholic Acid[1] CHOLIC ACID; [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310 💬
11 Lumasiran 💬 [1] Lumasiran[1] LUMASIRAN; [1] HAO1 💬[4] Carbon metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Peroxisome 💬[1] 234 💬