Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Cellular senescence 💬
 [1] CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬 💬
2 Cellular senescence 💬
 [1] CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬 💬
3 Cellular senescence 💬
 [1] CACNA1D 💬 Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬 💬
4 Cellular senescence 💬
 [1] CACNA1D 💬 Isradipine 💬 Isradipine [1]  6  💬 💬
5 Cellular senescence 💬
 [1] CACNA1D 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬 💬
6 Cellular senescence 💬
 [1] CACNA1D 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬 💬
7 Cellular senescence 💬
 [1] CACNA1D 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬 💬
8 Cellular senescence 💬
 [1] CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬 💬
9 Cellular senescence 💬
 [1] CACNA1D 💬 Propiverine 💬 Propiverine [1] 226 💬 💬
10 Cellular senescence 💬
 [1] CACNA1D 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬 💬
11 Cellular senescence 💬
 [1] CACNA1D 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬 💬
12 Cellular senescence 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬 💬
13 Cellular senescence 💬
 [1] IL1A 💬 Bermekimab 💬 Bermekimab [1] 51 💬 💬
14 Cellular senescence 💬
 [1] IL1A 💬 Rilonacept 💬 Rilonacept [4] 51, 106, 107, 266 💬 💬
15 Cellular senescence 💬
 [2] IL1A, IL6 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
16 Cellular senescence 💬
 [1] IL6 💬 Olokizumab 💬 Olokizumab [2] 46, 96 💬 💬
17 Cellular senescence 💬
 [1] IL6 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
18 Cellular senescence 💬
 [1] IL6 💬 Siltuximab 💬 Siltuximab [2] 28, 331 💬 💬
19 Cellular senescence 💬
 [1] IL6 💬 Sirukumab 💬 Sirukumab [2] 41, 46 💬 💬
20 Cellular senescence 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
21 Cellular senescence 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
22 Cellular senescence 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
23 Cellular senescence 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
24 Cellular senescence 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
25 Cellular senescence 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
26 Cellular senescence 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
27 Cellular senescence 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
28 Cellular senescence 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
29 Cellular senescence 💬
 [1] MTOR 💬 Temsirolimus 💬 Temsirolimus [1] 13 💬 💬
30 Cellular senescence 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬 💬
31 Cellular senescence 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
32 Cellular senescence 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
33 Cellular senescence 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
34 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬
35 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus [1] 160 💬 💬
36 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
37 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
38 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin [2] 49, 222 💬 💬
39 Cellular senescence 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
40 Cellular senescence 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬 💬
41 Cellular senescence 💬
 [3] TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab [3] 51, 85, 222 💬 💬