Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CETP 💬 [1] Cholesterol metabolism Anacetrapib 💬 Anacetrapib [1] 79 💬
2 PCSK9 💬 [1] Cholesterol metabolism Alirocumab 💬 Alirocumab [1] 79 💬
3 PCSK9 💬 [1] Cholesterol metabolism Evolocumab 💬 Evolocumab [2] 79, 222 💬
4 PCSK9 💬 [1] Cholesterol metabolism Inclisiran 💬 Inclisiran [1] 79 💬
5 ANGPTL3 💬 [1] Cholesterol metabolism Evinacumab 💬 Evinacumab [1] 79 💬
6 APOC3 💬 [2] PPAR signaling pathway, Cholesterol metabolism Volanesorsen 💬 Volanesorsen [1] 265 💬
7 LIPA 💬 [3] Steroid biosynthesis, Lysosome, Cholesterol metabolism Sebelipase alfa 💬 Sebelipase alfa [1] 19 💬
8 SORT1 💬 [3] Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab [2] 2, 127 💬