Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
2 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
3 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
4 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
5 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
6 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
7 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
8 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
9 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
10 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A [1] PDE5A 💬 |
Sildenafil Sildenafil 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬 |
11 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Oxandrolone Oxandrolone 💬 |
Oxandrolone | 211 [2] 211, 285 💬 💬 |
12 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
13 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB [1] EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
14 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Sildenafil Sildenafil 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬 |
15 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
16 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
17 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
18 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬 |
Methylprednisolone Methylprednisolone 💬 |
Methylprednisolone | 002 [46] 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 💬 |
19 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬 |
Methylprednisolone hemisuccinate Methylprednisolone hemisuccinate 💬 |
Methylprednisolone hemisuccinate | 013 [7] 13, 49, 50, 51, 53, 97, 211 💬 💬 |
20 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬 |
Oxandrolone Oxandrolone 💬 |
Oxandrolone | 211 [2] 211, 285 💬 💬 |
21 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Oxandrolone Oxandrolone 💬 |
Oxandrolone | 211 [2] 211, 285 💬 💬 |
22 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
23 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
24 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
25 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Oxandrolone Oxandrolone 💬 |
Oxandrolone | 211 [2] 211, 285 💬 💬 |
26 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A [1] PDE5A 💬 |
Sildenafil Sildenafil 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬 |
27 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
28 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
29 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
30 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
31 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
32 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 💬 |
33 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
34 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA [1] EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |