Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
2 Alcoholism 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
3 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
4 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
5 Apelin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
6 Apelin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
7 Calcium signaling pathway 💬
 [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
8 Calcium signaling pathway 💬
 [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
9 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
10 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
11 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
12 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
13 Cortisol synthesis and secretion 💬
 [2] PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
14 Cortisol synthesis and secretion 💬
 [2] PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
15 Cushing syndrome 💬
 [3] PDE11A, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
16 Cushing syndrome 💬
 [3] PDE11A, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
17 Glucagon signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
18 Glucagon signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
19 Insulin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
20 Insulin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
21 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
22 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
23 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
24 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
25 Neuroactive ligand-receptor interaction 💬
 [2] ADORA1, ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
26 Neuroactive ligand-receptor interaction 💬
 [2] ADORA1, ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
27 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
28 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
29 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
30 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
31 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
32 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
33 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
34 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
35 Rap1 signaling pathway 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
36 Rap1 signaling pathway 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
37 Regulation of lipolysis in adipocytes 💬
 [2] ADORA1, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
38 Regulation of lipolysis in adipocytes 💬
 [2] ADORA1, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
39 Renin secretion 💬
 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
40 Renin secretion 💬
 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
41 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
42 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
43 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
44 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
45 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
46 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬

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