Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[1] DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
2 Alzheimer disease 💬
[3] CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
3 Biosynthesis of cofactors 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬 💬
4 Biosynthesis of cofactors 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬 💬
5 Calcium signaling pathway 💬
[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
6 Calcium signaling pathway 💬
[1] HRH2 💬 Cimetidine 💬 Cimetidine [2]  2 , 254 💬 💬
7 cAMP signaling pathway 💬
[3] CHRM1, CHRM2, DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
8 cGMP-PKG signaling pathway 💬
[3] ADRA2A, ADRA2B, ADRA2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
9 Chemical carcinogenesis - reactive oxygen species 💬
[1] HMOX1 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
10 Cholinergic synapse 💬
[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
11 Cocaine addiction 💬
[1] DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
12 Dopaminergic synapse 💬
[1] DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
13 Ferroptosis 💬
[1] HMOX1 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
14 Fluid shear stress and atherosclerosis 💬
[1] HMOX1 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
15 Gap junction 💬
[4] DRD2, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
16 Gastric acid secretion 💬
[1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
17 Gastric acid secretion 💬
[1] HRH2 💬 Cimetidine 💬 Cimetidine [2]  2 , 254 💬 💬
18 Glycine, serine and threonine metabolism 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬 💬
19 Glycine, serine and threonine metabolism 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬 💬
20 Hepatocellular carcinoma 💬
[1] HMOX1 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
21 HIF-1 signaling pathway 💬
[1] HMOX1 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
22 Inflammatory mediator regulation of TRP channels 💬
[4] HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
23 Insulin secretion 💬
[1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
24 Melanogenesis 💬
[1] MC1R 💬 Afamelanotide 💬 Afamelanotide [3] 159, 161, 254 💬 💬
25 Metabolic pathways 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬 💬
26 Metabolic pathways 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬 💬
27 Metabolic pathways 💬
[2] HMOX1, HMOX2 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
28 MicroRNAs in cancer 💬
[1] HMOX1 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
29 Mineral absorption 💬
[2] HMOX1, HMOX2 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
30 Neuroactive ligand-receptor interaction 💬
[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
31 Neuroactive ligand-receptor interaction 💬
[1] HRH2 💬 Cimetidine 💬 Cimetidine [2]  2 , 254 💬 💬
32 Neuroactive ligand-receptor interaction 💬
[1] MC1R 💬 Afamelanotide 💬 Afamelanotide [3] 159, 161, 254 💬 💬
33 Pancreatic secretion 💬
[1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
34 Parkinson disease 💬
[1] DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
35 Pathways in cancer 💬
[1] HMOX1 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
36 Pathways of neurodegeneration - multiple diseases 💬
[3] CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
37 PI3K-Akt signaling pathway 💬
[2] CHRM1, CHRM2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
38 Porphyrin metabolism 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬 💬
39 Porphyrin metabolism 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬 💬
40 Porphyrin metabolism 💬
[2] HMOX1, HMOX2 💬 Stannsoporfin 💬 Stannsoporfin [1] 254 💬 💬
41 Rap1 signaling pathway 💬
[1] DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
42 Regulation of actin cytoskeleton 💬
[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
43 Salivary secretion 💬
[1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
44 Serotonergic synapse 💬
[3] HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
45 Taste transduction 💬
[1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬