Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
2 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
3 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
4 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
5 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F10 [2] F10, F9 💬 |
Emicizumab Emicizumab 💬 |
Emicizumab | 288 [1] 288 💬 💬 |
6 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
F8 [1] F8 💬 |
Desmopressin Desmopressin 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 💬 |
7 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
PLG [1] PLG 💬 |
Tranexamic acid Tranexamic acid 💬 |
Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬 💬 |
8 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL11RA [1] IL11RA 💬 |
Oprelvekin Oprelvekin 💬 |
Oprelvekin | 096 [2] 96, 288 💬 💬 |
9 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL11RA [1] IL11RA 💬 |
Oprelvekin Oprelvekin 💬 |
Oprelvekin | 096 [2] 96, 288 💬 💬 |
10 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 [1] MS4A1 💬 |
Rituximab Rituximab 💬 |
Rituximab | 011 [48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 💬 |
11 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
12 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
PLG [1] PLG 💬 |
Tranexamic acid Tranexamic acid 💬 |
Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬 💬 |
13 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL11RA [1] IL11RA 💬 |
Oprelvekin Oprelvekin 💬 |
Oprelvekin | 096 [2] 96, 288 💬 💬 |
14 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
15 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AVPR2 [1] AVPR2 💬 |
Desmopressin Desmopressin 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 💬 |
16 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬 |
Prednisone Prednisone 💬 |
Prednisone | 002 [45] 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 💬 |
17 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PLG [1] PLG 💬 |
Tranexamic acid Tranexamic acid 💬 |
Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬 💬 |
18 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
19 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
20 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AVPR2 [1] AVPR2 💬 |
Desmopressin Desmopressin 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 💬 |
21 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
22 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 20 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
23 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PSMB5 [1] PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
24 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
PLG [1] PLG 💬 |
Tranexamic acid Tranexamic acid 💬 |
Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬 💬 |
25 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
26 | Vasopressin-regulated water reabsorption 💬 1 gene, 6 drugs (DrugBank) and 10 diseases |
AVPR2 [1] AVPR2 💬 |
Desmopressin Desmopressin 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 💬 |