Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
RARA [1] RARA 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
6 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
7 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
8 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
9 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
10 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
11 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
12 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
13 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
14 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
15 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
16 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL17RA [1] IL17RA 💬 |
Brodalumab Brodalumab 💬 |
Brodalumab | 037 [2] 37, 51 💬 💬 |
17 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
18 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
19 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
20 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
21 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
22 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
23 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
24 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
25 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
26 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
27 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
28 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
29 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
30 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
31 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
32 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
33 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
34 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
35 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
36 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
37 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
38 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
39 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
40 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
41 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
42 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
43 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
44 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
45 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
46 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
47 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
RXRA [1] RXRA 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
48 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
49 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
50 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
51 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
52 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
53 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
54 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
55 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD58 [1] CD58 💬 |
Alefacept Alefacept 💬 |
Alefacept | 037 [6] 37, 60, 65, 164, 284, 285 💬 💬 |
56 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
57 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
58 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
59 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
60 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
61 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
62 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
63 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
Melatonin Melatonin 💬 |
Melatonin | 006 [12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬 💬 |
64 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
65 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
66 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
67 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
68 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
69 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
70 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
71 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17RA [1] IL17RA 💬 |
Brodalumab Brodalumab 💬 |
Brodalumab | 037 [2] 37, 51 💬 💬 |
72 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
73 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1RL2 [1] IL1RL2 💬 |
Imsidolimab Imsidolimab 💬 |
Imsidolimab | 037 [1] 37 💬 💬 |
74 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1RL2 [1] IL1RL2 💬 |
Spesolimab Spesolimab 💬 |
Spesolimab | 037 [3] 37, 96, 97 💬 💬 |
75 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
76 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
77 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
78 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
79 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
80 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
81 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
82 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
83 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
84 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
HPRT1 [1] HPRT1 💬 |
Tioguanine Tioguanine 💬 |
Tioguanine | 013 [2] 13, 37 💬 💬 |
85 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
86 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
CD58 [1] CD58 💬 |
Alefacept Alefacept 💬 |
Alefacept | 037 [6] 37, 60, 65, 164, 284, 285 💬 💬 |
87 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
88 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
89 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
90 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
91 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
RARA [1] RARA 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
92 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
93 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
94 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
95 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
96 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
97 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
98 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
99 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
RARB [4] RARB, RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
100 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
101 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
102 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
103 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
104 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
105 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
106 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
107 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
108 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
109 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
110 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
RXRA [1] RXRA 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
111 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
112 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
113 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
114 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
115 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
116 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
117 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
118 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
119 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
120 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
121 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
122 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
123 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
124 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
125 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
126 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
127 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
128 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
129 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
130 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
131 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
132 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
133 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
134 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
135 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
136 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
137 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
138 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17RA [1] IL17RA 💬 |
Brodalumab Brodalumab 💬 |
Brodalumab | 037 [2] 37, 51 💬 💬 |
139 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
140 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
141 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
142 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
143 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
144 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
145 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
146 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
147 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
148 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
149 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
150 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
151 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
152 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
153 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
154 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
155 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
156 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
157 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
158 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
159 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
160 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
161 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
162 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
163 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
164 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
165 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
166 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
167 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
168 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
169 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
170 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
171 | Leukocyte transendothelial migration 💬 13 genes, 14 drugs (DrugBank) and 30 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
172 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
173 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
174 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
175 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
176 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
177 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL12A [1] IL12A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
178 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
179 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
180 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
181 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
182 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
183 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
184 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
185 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
186 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
187 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPRT1 [1] HPRT1 💬 |
Tioguanine Tioguanine 💬 |
Tioguanine | 013 [2] 13, 37 💬 💬 |
188 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
189 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
190 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
191 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
192 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
193 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
194 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
195 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
196 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
197 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
198 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
199 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
Melatonin Melatonin 💬 |
Melatonin | 006 [12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬 💬 |
200 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
201 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
202 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
203 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
204 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
205 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
206 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
207 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
208 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
RXRA [1] RXRA 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
209 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
210 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
211 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
212 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB [4] RARB, RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
213 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
HPRT1 [1] HPRT1 💬 |
Tioguanine Tioguanine 💬 |
Tioguanine | 013 [2] 13, 37 💬 💬 |
214 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
215 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
216 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
217 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
218 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
219 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
220 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
221 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
222 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
223 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
224 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
225 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
226 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
227 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
228 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
RARA [5] RARA, RARB, RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
229 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
230 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
231 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
232 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
233 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
234 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
235 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
236 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
237 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
238 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
239 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
RXRA [1] RXRA 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
240 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
241 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
242 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
243 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
244 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 [1] IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
245 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IL12B [1] IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
246 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
247 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
248 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
249 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
HPRT1 [1] HPRT1 💬 |
Tioguanine Tioguanine 💬 |
Tioguanine | 013 [2] 13, 37 💬 💬 |
250 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
251 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
252 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
253 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
254 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
255 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
256 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
257 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A [1] IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
258 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
259 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
260 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
261 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
262 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
263 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
264 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
265 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
266 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
267 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
268 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
269 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
270 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
271 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
272 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
273 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB [4] RARB, RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
274 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
275 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
276 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
277 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
278 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
279 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
280 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
281 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
282 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
283 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
284 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
285 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
286 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
287 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
288 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
289 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
290 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 [1] IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
291 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
292 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
293 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
294 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
295 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA [4] RARA, RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
296 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
297 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
RXRA [3] RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
298 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
299 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
300 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
301 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
302 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
303 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
304 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
305 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
306 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
307 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
308 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
309 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL1R2 [1] IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
310 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
RARA [4] RARA, RXRA, RXRB, RXRG 💬 |
Acitretin Acitretin 💬 |
Acitretin | 037 [1] 37 💬 💬 |
311 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
312 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL23A [1] IL23A 💬 |
Guselkumab Guselkumab 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 💬 |
313 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL23A [1] IL23A 💬 |
Mirikizumab Mirikizumab 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 💬 |
314 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL23A [1] IL23A 💬 |
Risankizumab Risankizumab 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 💬 |
315 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
316 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
317 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
318 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬 |
Calcitriol Calcitriol 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 💬 |
319 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL12A [2] IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
320 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
321 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
322 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
323 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
324 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
325 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
326 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ITGAL [1] ITGAL 💬 |
Efalizumab Efalizumab 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬 |
327 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
328 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
329 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
330 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
331 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
332 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |