Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
KIT [1] KIT 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
4 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FGFR1 [1] FGFR1 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
5 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
6 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
7 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
8 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
9 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
10 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
11 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
12 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
13 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
14 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
15 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
16 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
17 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
18 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
19 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
20 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
21 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
22 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
23 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
24 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
25 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
ABL1 [2] ABL1, SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
26 | Bacterial invasion of epithelial cells 💬 5 genes, 7 drugs (DrugBank) and 13 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
27 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
28 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
FGFR3 [1] FGFR3 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
29 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
30 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
FGFR1 [2] FGFR1, FLT4 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
31 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
KIT [1] KIT 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
32 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
33 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
34 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
35 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
36 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
37 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
38 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HRH1 [1] HRH1 💬 |
Loratadine Loratadine 💬 |
Loratadine | 013 [4] 13, 46, 89, 98 💬 💬 |
39 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
40 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
41 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR2 [1] SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 💬 |
42 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
43 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
44 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
45 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
46 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
47 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
48 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
49 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
50 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
51 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
52 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
53 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
ABL1 [2] ABL1, SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
54 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
55 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
56 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
57 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
58 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
59 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
60 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
61 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
62 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
63 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
64 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
65 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
66 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
67 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
68 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
69 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
FGFR2 [5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
70 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
71 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
72 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
73 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
74 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
75 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
76 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
77 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
FGFR2 [3] FGFR2, FGFR3, PDGFRA 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
78 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
79 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
80 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
81 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
82 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
83 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
84 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
85 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
86 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
87 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
88 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
89 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
90 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
91 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
92 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
93 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
94 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
95 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
SSTR2 [1] SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 💬 |
96 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
FGFR2 [1] FGFR2 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
97 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
98 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
99 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
100 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
101 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
102 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
103 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
104 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
105 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
106 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
SSTR2 [1] SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 💬 |
107 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
KIT [1] KIT 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
108 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
109 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
110 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
111 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
112 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
113 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
114 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
115 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
116 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
117 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
118 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
119 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
120 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PDGFRA [1] PDGFRA 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
121 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
122 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
123 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
124 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
125 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
126 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
127 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB [1] PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
128 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
129 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
130 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
131 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
132 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HRH1 [1] HRH1 💬 |
Loratadine Loratadine 💬 |
Loratadine | 013 [4] 13, 46, 89, 98 💬 💬 |
133 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
134 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
135 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
136 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
137 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
138 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
139 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
140 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
141 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
142 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
143 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
144 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
145 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
146 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
147 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
148 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
149 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
150 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
151 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
152 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
153 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
154 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT [1] KIT 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
155 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGFR1 [3] FGFR1, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
156 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
157 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP19A1 [1] CYP19A1 💬 |
Letrozole Letrozole 💬 |
Letrozole | 081 [2] 81, 89 💬 💬 |
158 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
159 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
160 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
161 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
ABL1 [2] ABL1, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
162 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
FGFR3 [3] FGFR3, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
163 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
164 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
165 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
166 | Mitophagy - animal 💬 2 genes, 4 drugs (DrugBank) and 8 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
167 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
168 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
169 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
170 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HRH1 [1] HRH1 💬 |
Loratadine Loratadine 💬 |
Loratadine | 013 [4] 13, 46, 89, 98 💬 💬 |
171 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
SSTR2 [1] SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 💬 |
172 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
173 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
174 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
175 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
176 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
177 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
178 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
CYP19A1 [1] CYP19A1 💬 |
Letrozole Letrozole 💬 |
Letrozole | 081 [2] 81, 89 💬 💬 |
179 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
180 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
181 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
182 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
183 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
184 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
FGFR1 [1] FGFR1 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
185 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
186 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
ABL1 [2] ABL1, SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
187 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
188 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
189 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
FGFR1 [6] FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
190 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
191 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
192 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
193 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
194 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
195 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
196 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
197 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
198 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
199 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
200 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
201 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
202 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
203 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
204 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
205 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
206 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
207 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
208 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
FGFR1 [4] FGFR1, FGFR2, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
209 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
210 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
211 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
212 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [2] FGFR1, KDR 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
213 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
214 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
215 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
216 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
217 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KIT [2] KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
218 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
219 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
220 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
221 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
222 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
223 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
224 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
225 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
226 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
227 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
228 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
229 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
230 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
FLT1 [1] FLT1 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
231 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
232 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
233 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
234 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
235 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
236 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
237 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
238 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
239 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
240 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
CYP19A1 [1] CYP19A1 💬 |
Letrozole Letrozole 💬 |
Letrozole | 081 [2] 81, 89 💬 💬 |
241 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
242 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
243 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
244 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
FGFR1 [1] FGFR1 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
245 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
246 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
247 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
248 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
249 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
250 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
251 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
252 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
FLT1 [1] FLT1 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
253 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
254 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
255 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
256 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
257 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
258 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
259 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
260 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
261 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
262 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
SRC [1] SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |