Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Alfuzosin 💬 Alfuzosin [1] 13 💬 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRA1A 💬 Silodosin 💬 Silodosin [2]  6 , 13 💬 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬 💬
4 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Methylergometrine 💬 Methylergometrine [1] 280 💬 💬
5 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine [3]  6 , 17, 58 💬 💬
6 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬 💬
7 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine [1] 22 💬 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin [1] 13 💬 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin [1]  6  💬 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol [4] 57, 86, 113, 210 💬 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Dipivefrin 💬 Dipivefrin [1]  6  💬 💬
12 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Droxidopa 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬 💬
13 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Ephedrine 💬 Ephedrine [1] 11 💬 💬
14 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Epinephrine 💬 Epinephrine [3] 46, 70, 96 💬 💬
15 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Noradrenaline 💬 Norepinephrine [2] 22, 296 💬 💬
16 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬 💬
17 Adrenergic signaling in cardiomyocytes 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬 💬
18 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Atenolol 💬 Atenolol [1] 167 💬 💬
19 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬 💬
20 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Celiprolol 💬 Celiprolol [1] 168 💬 💬
21 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Dobutamine 💬 Dobutamine [4] 57, 58, 86, 215 💬 💬
22 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Esmolol 💬 Esmolol [1] 58 💬 💬
23 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Metoprolol 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬 💬
24 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Nebivolol 💬 Nebivolol [4] 17, 85, 113, 167 💬 💬
25 Adrenergic signaling in cardiomyocytes 💬
 [2] ADRB1, ADRB2 💬 Nadolol 💬 Nadolol [1]  6  💬 💬
26 Adrenergic signaling in cardiomyocytes 💬
 [2] ADRB1, ADRB2 💬 Propranolol 💬 Propranolol [6]  6 , 158, 167, 227, 278, 296 💬 💬
27 Adrenergic signaling in cardiomyocytes 💬
 [2] ADRB1, ADRB2 💬 Timolol 💬 Timolol [2] 157, 227 💬 💬
28 Adrenergic signaling in cardiomyocytes 💬
 [2] ADRB1, ADRB2 💬 Timolol 💬 Timolol [2] 157, 227 💬 💬
29 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Clenbuterol 💬 Clenbuterol [5]  1 ,  2 ,  6 , 13, 256 💬 💬
30 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬 💬
31 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Isoxsuprine 💬 Isoxsuprine [1] 13 💬 💬
32 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Levosalbutamol 💬 Levosalbutamol [1] 49 💬 💬
33 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
34 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬 💬
35 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Terbutaline 💬 Terbutaline [1] 118 💬 💬
36 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Tulobuterol 💬 Tulobuterol [1]  6  💬 💬
37 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬 💬
38 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬 💬
39 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Irbesartan 💬 Irbesartan [4] 66, 167, 168, 222 💬 💬
40 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬
41 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬 💬
42 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬 💬
43 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Valsartan 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬 💬
44 Adrenergic signaling in cardiomyocytes 💬
 [2] AGTR1, AGTR2 💬 Angiotensin II 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬 💬
45 Adrenergic signaling in cardiomyocytes 💬
 [2] AGTR1, AGTR2 💬 Angiotensin II 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬 💬
46 Adrenergic signaling in cardiomyocytes 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬 💬
47 Adrenergic signaling in cardiomyocytes 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digoxin 💬 Digoxin [3]  8 , 46, 210 💬 💬
48 Adrenergic signaling in cardiomyocytes 💬
 [1] BCL2 💬 Venetoclax 💬 Venetoclax [1] 28 💬 💬
49 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬 💬
50 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬 💬
51 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬 💬
52 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine [1]  6  💬 💬
53 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬 💬
54 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬 💬
55 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬 💬
56 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬 💬
57 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine [1] 226 💬 💬
58 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬 💬
59 Adrenergic signaling in cardiomyocytes 💬
 [5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬 💬
60 Adrenergic signaling in cardiomyocytes 💬
 [2] CACNA2D1, CACNA2D2 💬 Mirogabalin 💬 Mirogabalin [1] 70 💬 💬
61 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin [5]  6 , 13, 19, 70, 298 💬 💬
62 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬 💬
63 Adrenergic signaling in cardiomyocytes 💬
 [1] KCNQ1 💬 Ezogabine 💬 Ezogabine [2]  2 , 144 💬 💬
64 Adrenergic signaling in cardiomyocytes 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
65 Adrenergic signaling in cardiomyocytes 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
66 Adrenergic signaling in cardiomyocytes 💬
 [1] MYH7 💬 Mavacamten 💬 Mavacamten [1] 58 💬 💬
67 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 💬
68 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Carbamazepine 💬 Carbamazepine [3]  6 , 13, 231 💬 💬
69 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Cifenline 💬 Cibenzoline [1] 58 💬 💬
70 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Eleclazine 💬 Eleclazine [1] 58 💬 💬
71 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Flecainide 💬 Flecainide [1]  6  💬 💬
72 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬 💬
73 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Levobupivacaine 💬 Levobupivacaine [1] 46 💬 💬
74 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Lidocaine 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
75 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
76 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬 💬
77 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬 💬
78 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Oxybuprocaine 💬 Oxybuprocaine [1]  6  💬 💬
79 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Phenytoin 💬 Phenytoin [1] 13 💬 💬
80 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Quinidine 💬 Quinidine [3]  2 ,  8 , 13 💬 💬
81 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬 💬
82 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Rufinamide 💬 Rufinamide [1] 144 💬 💬
83 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 Zonisamide 💬 Zonisamide [1]  6  💬 💬