Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[1] ADORA2A 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
2 Alcoholism 💬
[1] ADORA2A 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
3 Alcoholism 💬
[1] ADORA2A 💬 Istradefylline 💬 Istradefylline [1]  6  💬 💬
4 Alcoholism 💬
[1] ADORA2A 💬 Preladenant 💬 Preladenant [1]  6  💬 💬
5 Alcoholism 💬
[1] ADORA2A 💬 Regadenoson 💬 Regadenoson [1] 58 💬 💬
6 Alcoholism 💬
[1] ADORA2A 💬 Regadenoson 💬 Regadenoson [1] 58 💬 💬
7 Alcoholism 💬
[1] ADORA2A 💬 Tozadenant 💬 Tozadenant [1]  6  💬 💬
8 Alcoholism 💬
[2] ADORA2A, ADORA2B 💬 Adenosine 💬 Adenosine [3] 13, 58, 65 💬 💬
9 Alcoholism 💬
[2] ADORA2A, ADORA2B 💬 Adenosine phosphate 💬 Adenosine phosphate [1] 46 💬 💬
10 Alcoholism 💬
[1] ADORA2B 💬 Aminophylline 💬 Aminophylline [1] 63 💬 💬
11 Alcoholism 💬
[1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
12 Alcoholism 💬
[1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
13 Alcoholism 💬
[1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬 💬
14 Alcoholism 💬
[2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
15 Alcoholism 💬
[1] DDC 💬 Benserazide 💬 Benserazide [1]  6  💬 💬
16 Alcoholism 💬
[1] DDC 💬 Carbidopa 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬 💬
17 Alcoholism 💬
[1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬 💬
18 Alcoholism 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬 💬
19 Alcoholism 💬
[2] DRD1, DRD2 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬 💬
20 Alcoholism 💬
[2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬 💬
21 Alcoholism 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬 💬
22 Alcoholism 💬
[2] DRD1, DRD2 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬 💬
23 Alcoholism 💬
[2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬 💬
24 Alcoholism 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬 💬
25 Alcoholism 💬
[1] DRD2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
26 Alcoholism 💬
[1] DRD2 💬 Bromocriptine 💬 Bromocriptine [2]  6 , 74 💬 💬
27 Alcoholism 💬
[1] DRD2 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬 💬
28 Alcoholism 💬
[1] DRD2 💬 Cabergoline 💬 Cabergoline [3]  6 , 74, 75 💬 💬
29 Alcoholism 💬
[1] DRD2 💬 Cariprazine 💬 Cariprazine [1] 21 💬 💬
30 Alcoholism 💬
[1] DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
31 Alcoholism 💬
[1] DRD2 💬 Domperidone 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬 💬
32 Alcoholism 💬
[1] DRD2 💬 Domperidone maleate 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬 💬
33 Alcoholism 💬
[1] DRD2 💬 Haloperidol 💬 Haloperidol [1]  8  💬 💬
34 Alcoholism 💬
[1] DRD2 💬 Iloperidone 💬 Iloperidone [1]  6  💬 💬
35 Alcoholism 💬
[1] DRD2 💬 Lisuride 💬 Lisuride [2]  6 , 86 💬 💬
36 Alcoholism 💬
[1] DRD2 💬 Melperone 💬 Melperone [1]  6  💬 💬
37 Alcoholism 💬
[1] DRD2 💬 Metoclopramide 💬 Metoclopramide [2] 46, 51 💬 💬
38 Alcoholism 💬
[1] DRD2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬 💬
39 Alcoholism 💬
[1] DRD2 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬 💬
40 Alcoholism 💬
[1] DRD2 💬 Pimozide 💬 Pimozide [1]  2  💬 💬
41 Alcoholism 💬
[1] DRD2 💬 Piribedil 💬 Piribedil [1]  6  💬 💬
42 Alcoholism 💬
[1] DRD2 💬 Pramipexole 💬 Pramipexole [3]  2 ,  6 , 20 💬 💬
43 Alcoholism 💬
[1] DRD2 💬 Pridopidine 💬 Pridopidine [3]  2 ,  6 ,  8  💬 💬
44 Alcoholism 💬
[1] DRD2 💬 Quetiapine 💬 Quetiapine [2]  6 , 13 💬 💬
45 Alcoholism 💬
[1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
46 Alcoholism 💬
[1] DRD2 💬 Ropinirole 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬 💬
47 Alcoholism 💬
[1] DRD2 💬 Rotigotine 💬 Rotigotine [1]  6  💬 💬
48 Alcoholism 💬
[1] DRD2 💬 Sulpiride 💬 Sulpiride [2]  6 , 70 💬 💬
49 Alcoholism 💬
[1] DRD2 💬 Terguride 💬 Terguride [2] 51, 86 💬 💬
50 Alcoholism 💬
[1] DRD2 💬 Tiapride 💬 Tiapride [1]  8  💬 💬
51 Alcoholism 💬
[1] DRD2 💬 Trifluoperazine maleate 💬 Trifluoperazine [2] 283, 284 💬 💬
52 Alcoholism 💬
[1] DRD2 💬 Trifluoperazine 💬 Trifluoperazine [2] 283, 284 💬 💬
53 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
54 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬 💬
55 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
56 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
57 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
58 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬 💬
59 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
60 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
61 Alcoholism 💬
[11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬 💬
62 Alcoholism 💬
[1] MAOA 💬 Moclobemide 💬 Moclobemide [1]  6  💬 💬
63 Alcoholism 💬
[2] MAOA, MAOB 💬 Iproniazid 💬 Iproniazid [1]  6  💬 💬
64 Alcoholism 💬
[2] MAOA, MAOB 💬 Phenelzine 💬 Phenelzine [1]  6  💬 💬
65 Alcoholism 💬
[3] MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine [1] 97 💬 💬
66 Alcoholism 💬
[1] MAOB 💬 Rasagiline 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬 💬
67 Alcoholism 💬
[1] MAOB 💬 Rasagiline tartrate 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬 💬
68 Alcoholism 💬
[1] MAOB 💬 Safinamide 💬 Safinamide [2]  6 , 17 💬 💬
69 Alcoholism 💬
[1] MAOB 💬 Selegiline 💬 Selegiline [1]  6  💬 💬
70 Alcoholism 💬
[1] MAP2K1 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
71 Alcoholism 💬
[1] MAP2K1 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
72 Alcoholism 💬
[1] MAP2K1 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
73 Alcoholism 💬
[1] MAP2K1 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
74 Alcoholism 💬
[1] MAP2K1 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
75 Alcoholism 💬
[1] SLC18A2 💬 Deutetrabenazine 💬 Deutetrabenazine [1]  8  💬 💬
76 Alcoholism 💬
[1] SLC18A2 💬 Tetrabenazine 💬 Tetrabenazine [1]  8  💬 💬
77 Alcoholism 💬
[1] SLC18A2 💬 Valbenazine 💬 Valbenazine [1]  8  💬 💬
78 Alcoholism 💬
[1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬 💬
79 Alcoholism 💬
[1] SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬 💬
80 Alcoholism 💬
[1] SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬 💬
81 Alcoholism 💬
[1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬