Gene

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No.	KEGG PATHWAY	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Bile secretion 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	Digitoxin 💬	Digitoxin	[1] 299 💬 💬
2	Bile secretion 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	Digoxin 💬	Digoxin	[3] 8 , 46, 210 💬 💬
3	Bile secretion 💬	[1] CA2 💬	Acetazolamide 💬	Acetazolamide	[8] 13, 86, 90, 115, 154, 155, 225, 230 💬 💬
4	Bile secretion 💬	[1] CA2 💬	Dichlorphenamide 💬	Diclofenamide	[1] 114 💬 💬
5	Bile secretion 💬	[1] CA2 💬	Dorzolamide 💬	Dorzolamide	[1] 90 💬 💬
6	Bile secretion 💬	[1] CA2 💬	Topiramate 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬 💬
7	Bile secretion 💬	[1] CFTR 💬	Deutivacaftor 💬	Deutivacaftor	[1] 299 💬 💬
8	Bile secretion 💬	[1] CFTR 💬	Elexacaftor 💬	Elexacaftor	[1] 299 💬 💬
9	Bile secretion 💬	[1] CFTR 💬	Galicaftor 💬	Galicaftor	[1] 299 💬 💬
10	Bile secretion 💬	[1] CFTR 💬	Ivacaftor 💬	Ivacaftor	[1] 299 💬 💬
11	Bile secretion 💬	[1] CFTR 💬	Lumacaftor 💬	Lumacaftor	[1] 299 💬 💬
12	Bile secretion 💬	[1] CFTR 💬	Tezacaftor 💬	Tezacaftor	[1] 299 💬 💬
13	Bile secretion 💬	[1] HMGCR 💬	Atorvastatin 💬	Atorvastatin	[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬
14	Bile secretion 💬	[1] HMGCR 💬	Fluvastatin 💬	Fluvastatin	[3] 79, 218, 222 💬 💬
15	Bile secretion 💬	[1] HMGCR 💬	Lovastatin 💬	Lovastatin	[11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
16	Bile secretion 💬	[1] HMGCR 💬	Pravastatin 💬	Pravastatin	[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬
17	Bile secretion 💬	[1] HMGCR 💬	Rosuvastatin 💬	Rosuvastatin	[11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 💬
18	Bile secretion 💬	[1] HMGCR 💬	Simvastatin 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬
19	Bile secretion 💬	[1] NR1H4 💬	Chenodiol 💬	Chenodeoxycholic acid	[4] 20, 96, 234, 263 💬 💬
20	Bile secretion 💬	[1] NR1H4 💬	Cholic acid 💬	Cholic Acid	[4] 20, 234, 265, 310 💬 💬
21	Bile secretion 💬	[1] NR1H4 💬	Obeticholic acid 💬	Obeticholic acid	[3] 93, 265, 296 💬 💬
22	Bile secretion 💬	[1] NR1H4 💬	Tropifexor 💬	Tropifexor	[1] 93 💬 💬
23	Bile secretion 💬	[1] NR1H4 💬	Ursodiol 💬	Ursodeoxycholic acid	[14] 6 , 8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬 💬
24	Bile secretion 💬	[1] RXRA 💬	Acitretin 💬	Acitretin	[1] 37 💬 💬
25	Bile secretion 💬	[1] RXRA 💬	Alitretinoin 💬	Alitretinoin	[1] 49 💬 💬
26	Bile secretion 💬	[1] RXRA 💬	Bexarotene 💬	Bexarotene	[2] 13, 75 💬 💬
27	Bile secretion 💬	[2] SLC10A1, SLC10A2 💬	Maralixibat 💬	Maralixibat	[3] 296, 297, 338 💬 💬
28	Bile secretion 💬	[1] SLC10A2 💬	Elobixibat 💬	Elobixibat	[1] 6 💬 💬
29	Bile secretion 💬	[1] SLC10A2 💬	Odevixibat 💬	Odevixibat	[3] 296, 297, 338 💬 💬