Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Breast cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬 💬
2 Breast cancer 💬
 [4] BRAF, FLT4, KIT, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
3 Breast cancer 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬 💬
4 Breast cancer 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬 💬
5 Breast cancer 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬 💬
6 Breast cancer 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬 💬
7 Breast cancer 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬 💬
8 Breast cancer 💬
 [2] EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬 💬
9 Breast cancer 💬
 [2] EGFR, ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬 💬
10 Breast cancer 💬
 [3] EGFR, ERBB2, FLT4 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬 💬
11 Breast cancer 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬 💬
12 Breast cancer 💬
 [2] ESR1, ESR2 💬 Clomifene 💬 Clomifene [1] 74 💬 💬
13 Breast cancer 💬
 [2] ESR1, ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬 💬
14 Breast cancer 💬
 [2] ESR1, ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬 💬
15 Breast cancer 💬
 [2] ESR1, ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬 💬
16 Breast cancer 💬
 [2] ESR1, ESR2 💬 Estradiol valerate 💬 Estradiol valerate [1] 65 💬 💬
17 Breast cancer 💬
 [2] ESR1, ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬 💬
18 Breast cancer 💬
 [2] ESR1, ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬 💬
19 Breast cancer 💬
 [2] ESR1, ESR2 💬 Fulvestrant 💬 Fulvestrant [2] 49, 86 💬 💬
20 Breast cancer 💬
 [2] ESR1, ESR2 💬 Mestranol 💬 Mestranol [2] 46, 49 💬 💬
21 Breast cancer 💬
 [2] ESR1, ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬 💬
22 Breast cancer 💬
 [2] ESR1, ESR2 💬 Raloxifene 💬 Raloxifene [1] 46 💬 💬
23 Breast cancer 💬
 [2] ESR1, ESR2 💬 Tamoxifen 💬 Tamoxifen [3]  2 , 113, 227 💬 💬
24 Breast cancer 💬
 [2] ESR1, PGR 💬 Danazol 💬 Danazol [5] 60, 63, 64, 65, 285 💬 💬
25 Breast cancer 💬
 [2] ESR1, PGR 💬 Desogestrel 💬 Desogestrel [1] 230 💬 💬
26 Breast cancer 💬
 [1] FGF23 💬 Burosumab 💬 Burosumab [1] 238 💬 💬
27 Breast cancer 💬
 [1] FGFR1 💬 Infigratinib 💬 Infigratinib [1] 276 💬 💬
28 Breast cancer 💬
 [2] FGFR1, FLT4 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬 💬
29 Breast cancer 💬
 [1] FLT4 💬 Axitinib 💬 Axitinib [1] 34 💬 💬
30 Breast cancer 💬
 [1] FLT4 💬 Cediranib 💬 Cediranib [1] 34 💬 💬
31 Breast cancer 💬
 [2] FLT4, KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬 💬
32 Breast cancer 💬
 [1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬 💬
33 Breast cancer 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬 💬
34 Breast cancer 💬
 [1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬 💬
35 Breast cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
36 Breast cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
37 Breast cancer 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
38 Breast cancer 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬 💬
39 Breast cancer 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬 💬
40 Breast cancer 💬
 [1] KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬 💬
41 Breast cancer 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
42 Breast cancer 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
43 Breast cancer 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
44 Breast cancer 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
45 Breast cancer 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
46 Breast cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
47 Breast cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
48 Breast cancer 💬
 [1] MTOR 💬 Temsirolimus 💬 Temsirolimus [1] 13 💬 💬
49 Breast cancer 💬
 [1] PGR 💬 Dydrogesterone 💬 Dydrogesterone [1] 13 💬 💬
50 Breast cancer 💬
 [1] PGR 💬 Levonorgestrel 💬 Levonorgestrel [1] 13 💬 💬
51 Breast cancer 💬
 [1] PGR 💬 Medroxyprogesterone acetate 💬 Medroxyprogesterone acetate [8] 13, 35, 46, 49, 50, 51, 60, 107 💬 💬
52 Breast cancer 💬
 [1] PGR 💬 Megestrol acetate 💬 Megestrol acetate [1] 76 💬 💬
53 Breast cancer 💬
 [1] PGR 💬 Mifepristone 💬 Mifepristone [1] 75 💬 💬
54 Breast cancer 💬
 [1] PGR 💬 Nomegestrol 💬 Nomegestrol [1] 13 💬 💬
55 Breast cancer 💬
 [1] PGR 💬 Nomegestrol acetate 💬 Nomegestrol acetate [1] 13 💬 💬
56 Breast cancer 💬
 [1] PGR 💬 Norethindrone 💬 Norethisterone [4] 13, 46, 49, 299 💬 💬
57 Breast cancer 💬
 [1] PGR 💬 Norgestimate 💬 Norgestimate [1] 299 💬 💬
58 Breast cancer 💬
 [1] PGR 💬 Progesterone 💬 Progesterone [2] 76, 299 💬 💬
59 Breast cancer 💬
 [1] PGR 💬 Ulipristal 💬 Ulipristal [1] 10 💬 💬
60 Breast cancer 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
61 Breast cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
62 Breast cancer 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
63 Breast cancer 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬 💬