Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Chronic myeloid leukemia 💬
[1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬 💬
2 Chronic myeloid leukemia 💬
[1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
3 Chronic myeloid leukemia 💬
[1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
4 Chronic myeloid leukemia 💬
[1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
5 Chronic myeloid leukemia 💬
[1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬 💬
6 Chronic myeloid leukemia 💬
[1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬 💬
7 Chronic myeloid leukemia 💬
[1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬 💬
8 Chronic myeloid leukemia 💬
[2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
9 Chronic myeloid leukemia 💬
[2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬 💬
10 Chronic myeloid leukemia 💬
[2] HDAC1, HDAC2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬 💬
11 Chronic myeloid leukemia 💬
[2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
12 Chronic myeloid leukemia 💬
[2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
13 Chronic myeloid leukemia 💬
[2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
14 Chronic myeloid leukemia 💬
[2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
15 Chronic myeloid leukemia 💬
[2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
16 Chronic myeloid leukemia 💬
[1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬 💬
17 Chronic myeloid leukemia 💬
[1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
18 Chronic myeloid leukemia 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
19 Chronic myeloid leukemia 💬
[1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
20 Chronic myeloid leukemia 💬
[1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬 💬
21 Chronic myeloid leukemia 💬
[3] TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab [3] 51, 85, 222 💬 💬