Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬 💬
2 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬 💬
3 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬 💬
4 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Isradipine 💬 Isradipine [1]  6  💬 💬
5 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬 💬
6 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬 💬
7 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬 💬
8 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬 💬
9 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Propiverine 💬 Propiverine [1] 226 💬 💬
10 Circadian entrainment 💬
[2] CACNA1C, CACNA1D 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬 💬
11 Circadian entrainment 💬
[6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬 💬
12 Circadian entrainment 💬
[3] CACNA1G, CACNA1H, CACNA1I 💬 Flunarizine 💬 Flunarizine [1] 149 💬 💬
13 Circadian entrainment 💬
[3] CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬
14 Circadian entrainment 💬
[3] CACNA1G, CACNA1H, CACNA1I 💬 Zonisamide 💬 Zonisamide [1]  6  💬 💬
15 Circadian entrainment 💬
[4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬 💬
16 Circadian entrainment 💬
[4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬 💬
17 Circadian entrainment 💬
[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
18 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
19 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬 💬
20 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
21 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
22 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
23 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬 💬
24 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
25 Circadian entrainment 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite [1] 58 💬 💬
26 Circadian entrainment 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬 💬
27 Circadian entrainment 💬
[2] KCNJ3, KCNJ5 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬 💬
28 Circadian entrainment 💬
[2] MTNR1A, MTNR1B 💬 Agomelatine 💬 Agomelatine [1]  6  💬 💬
29 Circadian entrainment 💬
[2] MTNR1A, MTNR1B 💬 Melatonin 💬 Melatonin [12]  6 ,  8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬 💬
30 Circadian entrainment 💬
[2] MTNR1A, MTNR1B 💬 Ramelteon 💬 Ramelteon [3]  6 ,  8 , 46 💬 💬
31 Circadian entrainment 💬
[2] MTNR1A, MTNR1B 💬 Tasimelteon 💬 Tasimelteon [1] 202 💬 💬
32 Circadian entrainment 💬
[1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬 💬