Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Complement and coagulation cascades 💬
 [3] C1R, C1S, KLKB1 💬 Conestat alfa 💬 Conestat alfa [1] 61 💬 💬
2 Complement and coagulation cascades 💬
 [1] C1S 💬 Sutimlimab 💬 Sutimlimab [1] 61 💬 💬
3 Complement and coagulation cascades 💬
 [1] C3 💬 Pegcetacoplan 💬 Pegcetacoplan [4]  2 , 61, 62, 222 💬 💬
4 Complement and coagulation cascades 💬
 [1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬 💬
5 Complement and coagulation cascades 💬
 [1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬 💬
6 Complement and coagulation cascades 💬
 [1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬 💬
7 Complement and coagulation cascades 💬
 [1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬 💬
8 Complement and coagulation cascades 💬
 [1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬 💬
9 Complement and coagulation cascades 💬
 [1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬 💬
10 Complement and coagulation cascades 💬
 [1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬 💬
11 Complement and coagulation cascades 💬
 [1] C5AR1 💬 Avacopan 💬 Avacopan [3] 43, 44, 222 💬 💬
12 Complement and coagulation cascades 💬
 [1] CFB 💬 Iptacopan 💬 Iptacopan [5] 61, 62, 66, 109, 222 💬 💬
13 Complement and coagulation cascades 💬
 [1] CFD 💬 Danicopan 💬 Danicopan [1] 62 💬 💬
14 Complement and coagulation cascades 💬
 [1] F10 💬 Apixaban 💬 Apixaban [1] 222 💬 💬
15 Complement and coagulation cascades 💬
 [1] F10 💬 Edoxaban 💬 Edoxaban [2] 46, 88 💬 💬
16 Complement and coagulation cascades 💬
 [1] F10 💬 Rivaroxaban 💬 Rivaroxaban [4] 46, 49, 91, 210 💬 💬
17 Complement and coagulation cascades 💬
 [2] F10, F9 💬 Emicizumab 💬 Emicizumab [1] 288 💬 💬
18 Complement and coagulation cascades 💬
 [1] F2 💬 Dabigatran 💬 Dabigatran [5] 51, 75, 85, 91, 124 💬 💬
19 Complement and coagulation cascades 💬
 [1] F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate [2] 51, 75 💬 💬
20 Complement and coagulation cascades 💬
 [1] F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa [1] 85 💬 💬
21 Complement and coagulation cascades 💬
 [1] F8 💬 Desmopressin 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬 💬
22 Complement and coagulation cascades 💬
 [1] MASP2 💬 Narsoplimab 💬 Narsoplimab [4] 64, 66, 109, 222 💬 💬
23 Complement and coagulation cascades 💬
 [1] PLG 💬 Aminocaproic acid 💬 Aminocaproic acid [1] 70 💬 💬
24 Complement and coagulation cascades 💬
 [1] PLG 💬 Tranexamic acid 💬 Tranexamic acid [7] 46, 70, 215, 227, 274, 288, 299 💬 💬
25 Complement and coagulation cascades 💬
 [1] SERPINC1 💬 Adomiparin 💬 Enoxaparin [1] 46 💬 💬
26 Complement and coagulation cascades 💬
 [1] SERPINC1 💬 Adomiparin 💬 Heparin [11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬 💬
27 Complement and coagulation cascades 💬
 [1] SERPINC1 💬 Adomiparin 💬 Parnaparin [1] 97 💬 💬
28 Complement and coagulation cascades 💬
 [2] SERPINC1, SERPIND1 💬 Sulodexide 💬 Sulodexide [2] 51, 271 💬 💬
29 Complement and coagulation cascades 💬
 [1] VWF 💬 Caplacizumab 💬 Caplacizumab [1] 64 💬 💬