Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Glioma 💬
[1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬 💬
2 Glioma 💬
[3] BRAF, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
3 Glioma 💬
[2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬 💬
4 Glioma 💬
[1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬 💬
5 Glioma 💬
[1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬 💬
6 Glioma 💬
[1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬 💬
7 Glioma 💬
[1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬 💬
8 Glioma 💬
[1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬 💬
9 Glioma 💬
[1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬 💬
10 Glioma 💬
[1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬 💬
11 Glioma 💬
[1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬 💬
12 Glioma 💬
[1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬 💬
13 Glioma 💬
[1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬 💬
14 Glioma 💬
[2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
15 Glioma 💬
[2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
16 Glioma 💬
[2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
17 Glioma 💬
[2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
18 Glioma 💬
[2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
19 Glioma 💬
[1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
20 Glioma 💬
[1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
21 Glioma 💬
[1] MTOR 💬 Temsirolimus 💬 Temsirolimus [1] 13 💬 💬
22 Glioma 💬
[1] PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
23 Glioma 💬
[2] PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬 💬
24 Glioma 💬
[2] PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬 💬
25 Glioma 💬
[2] PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬 💬
26 Glioma 💬
[1] PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
27 Glioma 💬
[1] PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
28 Glioma 💬
[1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
29 Glioma 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
30 Glioma 💬
[1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
31 Glioma 💬
[1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬 💬