Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬 💬
2 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬 💬
3 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬 💬
4 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine [1]  6  💬 💬
5 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬 💬
6 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬 💬
7 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬 💬
8 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬 💬
9 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine [1] 226 💬 💬
10 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬 💬
11 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬 💬
12 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 Lonapegsomatropin 💬 Lonapegsomatropin [1] 78 💬 💬
13 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬 💬
14 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 Pegvisomant 💬 Pegvisomant [2] 78, 265 💬 💬
15 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 Somapacitan 💬 Somapacitan [2] 78, 195 💬 💬
16 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 Somavaratan 💬 Somavaratan [1] 78 💬 💬
17 Growth hormone synthesis, secretion and action 💬
 [1] GHRHR 💬 Somatorelin 💬 Somatorelin [2] 13, 78 💬 💬
18 Growth hormone synthesis, secretion and action 💬
 [1] GHRHR 💬 Tesamorelin 💬 Tesamorelin [2] 78, 265 💬 💬
19 Growth hormone synthesis, secretion and action 💬
 [1] GHSR 💬 Macimorelin 💬 Macimorelin [1] 78 💬 💬
20 Growth hormone synthesis, secretion and action 💬
 [1] JAK2 💬 Baricitinib 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
21 Growth hormone synthesis, secretion and action 💬
 [1] JAK2 💬 Peficitinib 💬 Peficitinib [1] 46 💬 💬
22 Growth hormone synthesis, secretion and action 💬
 [1] JAK2 💬 Ruxolitinib 💬 Ruxolitinib [3] 60, 65, 228 💬 💬
23 Growth hormone synthesis, secretion and action 💬
 [1] JAK2 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
24 Growth hormone synthesis, secretion and action 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
25 Growth hormone synthesis, secretion and action 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
26 Growth hormone synthesis, secretion and action 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
27 Growth hormone synthesis, secretion and action 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
28 Growth hormone synthesis, secretion and action 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
29 Growth hormone synthesis, secretion and action 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
30 Growth hormone synthesis, secretion and action 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
31 Growth hormone synthesis, secretion and action 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
32 Growth hormone synthesis, secretion and action 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
33 Growth hormone synthesis, secretion and action 💬
 [1] MTOR 💬 Temsirolimus 💬 Temsirolimus [1] 13 💬 💬
34 Growth hormone synthesis, secretion and action 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
35 Growth hormone synthesis, secretion and action 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
36 Growth hormone synthesis, secretion and action 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
37 Growth hormone synthesis, secretion and action 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬 💬
38 Growth hormone synthesis, secretion and action 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
39 Growth hormone synthesis, secretion and action 💬
 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬 💬
40 Growth hormone synthesis, secretion and action 💬
 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Somatostatin 💬 Somatostatin [2] 67, 78 💬 💬
41 Growth hormone synthesis, secretion and action 💬
 [1] SSTR2 💬 Octreotide 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬 💬