Gene

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No.	KEGG PATHWAY	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Hepatocellular carcinoma 💬	[1] BRAF 💬	Dabrafenib 💬	Dabrafenib	[1] 34 💬 💬
2	Hepatocellular carcinoma 💬	[2] BRAF, RAF1 💬	Sorafenib 💬	Sorafenib	[2] 34, 86 💬 💬
3	Hepatocellular carcinoma 💬	[2] CDK4, CDK6 💬	Abemaciclib 💬	Abemaciclib	[1] 34 💬 💬
4	Hepatocellular carcinoma 💬	[1] EGFR 💬	Cetuximab 💬	Cetuximab	[2] 51, 86 💬 💬
5	Hepatocellular carcinoma 💬	[1] EGFR 💬	Erlotinib 💬	Erlotinib	[1] 94 💬 💬
6	Hepatocellular carcinoma 💬	[1] EGFR 💬	Gefitinib 💬	Gefitinib	[1] 75 💬 💬
7	Hepatocellular carcinoma 💬	[1] EGFR 💬	Icotinib 💬	Icotinib	[1] 34 💬 💬
8	Hepatocellular carcinoma 💬	[1] EGFR 💬	Lapatinib 💬	Lapatinib	[3] 34, 74, 75 💬 💬
9	Hepatocellular carcinoma 💬	[1] EGFR 💬	Neratinib 💬	Neratinib	[1] 34 💬 💬
10	Hepatocellular carcinoma 💬	[1] EGFR 💬	Tesevatinib 💬	Tesevatinib	[1] 67 💬 💬
11	Hepatocellular carcinoma 💬	[1] HMOX1 💬	Stannsoporfin 💬	Stannsoporfin	[1] 254 💬 💬
12	Hepatocellular carcinoma 💬	[1] IGF1R 💬	Linsitinib 💬	Linsitinib	[1] 232 💬 💬
13	Hepatocellular carcinoma 💬	[1] IGF1R 💬	Mecasermin 💬	Mecasermin	[6] 65, 78, 96, 168, 265, 299 💬 💬
14	Hepatocellular carcinoma 💬	[1] IGF1R 💬	Teprotumumab 💬	Teprotumumab	[1] 51 💬 💬
15	Hepatocellular carcinoma 💬	[1] KEAP1 💬	Dimethyl fumarate 💬	Dimethyl fumarate	[5] 13, 49, 51, 86, 296 💬 💬
16	Hepatocellular carcinoma 💬	[2] MAP2K1, MAP2K2 💬	Binimetinib 💬	Binimetinib	[1] 34 💬 💬
17	Hepatocellular carcinoma 💬	[2] MAP2K1, MAP2K2 💬	Cobimetinib 💬	Cobimetinib	[1] 280 💬 💬
18	Hepatocellular carcinoma 💬	[2] MAP2K1, MAP2K2 💬	Mirdametinib 💬	Mirdametinib	[1] 34 💬 💬
19	Hepatocellular carcinoma 💬	[2] MAP2K1, MAP2K2 💬	Selumetinib 💬	Selumetinib	[1] 34 💬 💬
20	Hepatocellular carcinoma 💬	[2] MAP2K1, MAP2K2 💬	Trametinib 💬	Trametinib	[4] 2 , 34, 279, 280 💬 💬
21	Hepatocellular carcinoma 💬	[1] MET 💬	Cabozantinib 💬	Cabozantinib	[1] 34 💬 💬
22	Hepatocellular carcinoma 💬	[1] MTOR 💬	Everolimus 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
23	Hepatocellular carcinoma 💬	[1] MTOR 💬	Sirolimus 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
24	Hepatocellular carcinoma 💬	[1] MTOR 💬	Temsirolimus 💬	Temsirolimus	[1] 13 💬 💬
25	Hepatocellular carcinoma 💬	[1] NFE2L2 💬	Omaveloxolone 💬	Omaveloxolone	[1] 18 💬 💬
26	Hepatocellular carcinoma 💬	[1] NQO1 💬	Warfarin 💬	Warfarin	[11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
27	Hepatocellular carcinoma 💬	[1] PIK3CA 💬	Alpelisib 💬	Alpelisib	[1] 138 💬 💬
28	Hepatocellular carcinoma 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	Leniolisib 💬	Leniolisib	[2] 53, 65 💬 💬
29	Hepatocellular carcinoma 💬	[1] PIK3CD 💬	Parsaclisib 💬	Parsaclisib	[3] 35, 53, 61 💬 💬
30	Hepatocellular carcinoma 💬	[1] PRKCB 💬	Enzastaurin 💬	Enzastaurin	[1] 168 💬 💬
31	Hepatocellular carcinoma 💬	[3] TGFB1, TGFB2, TGFB3 💬	Fresolimumab 💬	Fresolimumab	[3] 51, 85, 222 💬 💬