Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF [1] BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 [1] 34 💬
|
2 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF [3] BRAF, KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
3 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Cetuximab Cetuximab 💬
| Cetuximab | 051 [2] 51, 86 💬
|
4 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Erlotinib Erlotinib 💬
| Erlotinib | 094 [1] 94 💬
|
5 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Gefitinib Gefitinib 💬
| Gefitinib | 075 [1] 75 💬
|
6 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [1] EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 [1] 34 💬
|
7 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
8 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
9 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
10 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
11 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Danazol Danazol 💬
| Danazol | 060 [5] 60, 63, 64, 65, 285 💬
|
12 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Desogestrel Desogestrel 💬
| Desogestrel | 230 [1] 230 💬
|
13 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
14 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
15 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
16 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
17 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
18 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
19 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Ethinyl estradiol Ethinyl estradiol 💬
| Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬
|
20 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
21 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
22 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
23 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
24 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 [1] ESR1 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
25 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [1] FGFR1 💬
|
Infigratinib Infigratinib 💬
| Infigratinib | 276 [1] 276 💬
|
26 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [2] FGFR1, KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
27 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
28 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
29 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
30 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IL12B [1] IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
31 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
32 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
33 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
34 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
35 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
36 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
37 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
38 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
39 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
40 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 [2] 113, 222 💬
|
41 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 [1] 8 💬
|
42 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
43 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
44 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 [1] 13 💬
|
45 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PIK3CA [1] PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 [1] 138 💬
|
46 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 [2] 53, 65 💬
|
47 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PIK3CD [1] PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 [3] 35, 53, 61 💬
|
48 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
PRKCB [1] PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 [1] 168 💬
|
49 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ROCK1 [2] ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 [4] 2 , 5 , 7 , 51 💬
|
50 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ROCK2 [1] ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 [2] 51, 85 💬
|
51 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬
|
Taladegib Taladegib 💬
| Taladegib | 085 [1] 85 💬
|
52 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SMO [1] SMO 💬
|
Vismodegib Vismodegib 💬
| Vismodegib | 085 [1] 85 💬
|
53 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 [2] 2 , 67 💬
|
54 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
55 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 [2] 51, 85 💬
|
56 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
SRC [1] SRC 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 [3] 6 , 89, 272 💬
|
57 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TGFB1 [2] TGFB1, TGFB2 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 [3] 51, 85, 222 💬
|
58 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
59 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
|
60 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
61 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
62 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
63 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
|
64 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 [1] 46 💬
|
65 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 [1] 46 💬
|
66 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
67 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬
|
68 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
69 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬
|
Aflibercept Aflibercept 💬
| Aflibercept | 090 [2] 90, 166 💬
|
70 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬
|
71 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA [1] VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 [4] 34, 166, 227, 301 💬
|