Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Signaling pathways regulating pluripotency of stem cells 💬
 [1] ACVR2A 💬 Sotatercept 💬 Sotatercept [2] 86, 284 💬 💬
2 Signaling pathways regulating pluripotency of stem cells 💬
 [2] ACVR2A, ACVR2B 💬 Bimagrumab 💬 Bimagrumab [1] 15 💬 💬
3 Signaling pathways regulating pluripotency of stem cells 💬
 [1] ACVR2B 💬 Luspatercept 💬 Luspatercept [1] 60 💬 💬
4 Signaling pathways regulating pluripotency of stem cells 💬
 [3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬 💬
5 Signaling pathways regulating pluripotency of stem cells 💬
 [3] FGFR1, FGFR2, FGFR3 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬 💬
6 Signaling pathways regulating pluripotency of stem cells 💬
 [1] FGFR2 💬 Palifermin 💬 Palifermin [5] 13, 36, 38, 39, 65 💬 💬
7 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬 💬
8 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬 💬
9 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬 💬
10 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 Abrocitinib 💬 Abrocitinib [1] 84 💬 💬
11 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 Filgotinib 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬 💬
12 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 Itacitinib 💬 Itacitinib [4] 46, 51, 97, 228 💬 💬
13 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 Upadacitinib 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬
14 Signaling pathways regulating pluripotency of stem cells 💬
 [2] JAK1, JAK2 💬 Baricitinib 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
15 Signaling pathways regulating pluripotency of stem cells 💬
 [2] JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib [3] 60, 65, 228 💬 💬
16 Signaling pathways regulating pluripotency of stem cells 💬
 [3] JAK1, JAK2, JAK3 💬 Peficitinib 💬 Peficitinib [1] 46 💬 💬
17 Signaling pathways regulating pluripotency of stem cells 💬
 [3] JAK1, JAK2, JAK3 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
18 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
19 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
20 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
21 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
22 Signaling pathways regulating pluripotency of stem cells 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
23 Signaling pathways regulating pluripotency of stem cells 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
24 Signaling pathways regulating pluripotency of stem cells 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
25 Signaling pathways regulating pluripotency of stem cells 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
26 Signaling pathways regulating pluripotency of stem cells 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
27 Signaling pathways regulating pluripotency of stem cells 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
28 Signaling pathways regulating pluripotency of stem cells 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬