Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Axon guidance 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Axon guidance 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
3 Axon guidance 💬
 [4] ABL1, EPHA2, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
4 Axon guidance 💬
 [4] ABL1, EPHA2, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
5 Axon guidance 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
6 Axon guidance 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
7 Cell cycle 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
8 Cell cycle 💬
 [1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
9 Cell cycle 💬
 [1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
10 Cell cycle 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
11 Cell cycle 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
12 Cell cycle 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
13 Chemical carcinogenesis - reactive oxygen species 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
14 Chemical carcinogenesis - reactive oxygen species 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
15 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
16 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
17 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
18 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
19 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
20 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
21 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
22 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
23 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
24 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
25 ErbB signaling pathway 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
26 ErbB signaling pathway 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
27 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
28 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
29 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
30 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
31 MicroRNAs in cancer 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
32 MicroRNAs in cancer 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
33 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
34 MicroRNAs in cancer 💬
 [3] ABL1, PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
35 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
36 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
37 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
38 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
39 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
40 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
41 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
42 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
43 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
44 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
45 Pathogenic Escherichia coli infection 💬
 [3] ABL1, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
46 Pathogenic Escherichia coli infection 💬
 [3] ABL1, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
47 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
48 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
49 Pathways in cancer 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
50 Pathways in cancer 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
51 Pathways in cancer 💬
 [3] ABL1, KIT, PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
52 Pathways in cancer 💬
 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
53 Pathways in cancer 💬
 [3] ABL1, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
54 Pathways in cancer 💬
 [3] ABL1, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
55 Ras signaling pathway 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
56 Ras signaling pathway 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
57 Ras signaling pathway 💬
 [4] ABL1, EPHA2, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
58 Ras signaling pathway 💬
 [4] ABL1, EPHA2, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
59 Ras signaling pathway 💬
 [3] ABL1, KIT, PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
60 Ras signaling pathway 💬
 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
61 Viral myocarditis 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
62 Viral myocarditis 💬
 [1] ABL1 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
63 Viral myocarditis 💬
 [1] ABL1 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
64 Viral myocarditis 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
65 Viral myocarditis 💬
 [2] ABL1, FYN 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
66 Viral myocarditis 💬
 [2] ABL1, FYN 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬

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