Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Biosynthesis of cofactors 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬
2 Biosynthesis of cofactors 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬
3 Glycine, serine and threonine metabolism 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬
4 Glycine, serine and threonine metabolism 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬
5 Metabolic pathways 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬
6 Metabolic pathways 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬
7 Porphyrin metabolism 💬
[1] ALAS1 💬 Givosiran 💬 Givosiran [1] 254 💬
8 Porphyrin metabolism 💬
[2] ALAS1, ALAS2 💬 Hemin 💬 Hemin [1] 254 💬