Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 B cell receptor signaling pathway 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
2 B cell receptor signaling pathway 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
3 B cell receptor signaling pathway 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
4 B cell receptor signaling pathway 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
5 B cell receptor signaling pathway 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
6 B cell receptor signaling pathway 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
7 B cell receptor signaling pathway 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
8 B cell receptor signaling pathway 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
9 Epstein-Barr virus infection 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
10 Epstein-Barr virus infection 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
11 Epstein-Barr virus infection 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
12 Epstein-Barr virus infection 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
13 Epstein-Barr virus infection 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
14 Epstein-Barr virus infection 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
15 Epstein-Barr virus infection 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
16 Epstein-Barr virus infection 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
17 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
18 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
19 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
20 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
21 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
22 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
23 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
24 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
25 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
26 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
27 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
28 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
29 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
30 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
31 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
32 NF-kappa B signaling pathway 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
33 Osteoclast differentiation 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
34 Osteoclast differentiation 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
35 Osteoclast differentiation 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
36 Osteoclast differentiation 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
37 Osteoclast differentiation 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
38 Osteoclast differentiation 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
39 Osteoclast differentiation 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
40 Osteoclast differentiation 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
41 Platelet activation 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
42 Platelet activation 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
43 Platelet activation 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
44 Platelet activation 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
45 Platelet activation 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
46 Platelet activation 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
47 Platelet activation 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
48 Platelet activation 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
49 Primary immunodeficiency 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬
50 Primary immunodeficiency 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬
51 Primary immunodeficiency 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬
52 Primary immunodeficiency 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬
53 Primary immunodeficiency 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬
54 Primary immunodeficiency 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
55 Primary immunodeficiency 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬
56 Primary immunodeficiency 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬

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