Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholic liver disease 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
2 Alcoholic liver disease 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
3 Alcoholic liver disease 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
4 Alcoholic liver disease 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
5 Alcoholic liver disease 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
6 Alcoholic liver disease 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
7 Alcoholic liver disease 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
8 Alcoholic liver disease 💬
[1] C5AR1 💬 Avacopan 💬 Avacopan [3] 43, 44, 222 💬
9 Complement and coagulation cascades 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
10 Complement and coagulation cascades 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
11 Complement and coagulation cascades 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
12 Complement and coagulation cascades 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
13 Complement and coagulation cascades 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
14 Complement and coagulation cascades 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
15 Complement and coagulation cascades 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
16 Complement and coagulation cascades 💬
[1] C5AR1 💬 Avacopan 💬 Avacopan [3] 43, 44, 222 💬
17 Coronavirus disease - COVID-19 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
18 Coronavirus disease - COVID-19 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
19 Coronavirus disease - COVID-19 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
20 Coronavirus disease - COVID-19 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
21 Coronavirus disease - COVID-19 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
22 Coronavirus disease - COVID-19 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
23 Coronavirus disease - COVID-19 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
24 Coronavirus disease - COVID-19 💬
[1] C5AR1 💬 Avacopan 💬 Avacopan [3] 43, 44, 222 💬
25 Herpes simplex virus 1 infection 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
26 Herpes simplex virus 1 infection 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
27 Herpes simplex virus 1 infection 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
28 Herpes simplex virus 1 infection 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
29 Herpes simplex virus 1 infection 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
30 Herpes simplex virus 1 infection 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
31 Herpes simplex virus 1 infection 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
32 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
33 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
34 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
35 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
36 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
37 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
38 Neuroactive ligand-receptor interaction 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
39 Neuroactive ligand-receptor interaction 💬
[1] C5AR1 💬 Avacopan 💬 Avacopan [3] 43, 44, 222 💬
40 Neutrophil extracellular trap formation 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
41 Neutrophil extracellular trap formation 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
42 Neutrophil extracellular trap formation 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
43 Neutrophil extracellular trap formation 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
44 Neutrophil extracellular trap formation 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
45 Neutrophil extracellular trap formation 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
46 Neutrophil extracellular trap formation 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
47 Neutrophil extracellular trap formation 💬
[1] C5AR1 💬 Avacopan 💬 Avacopan [3] 43, 44, 222 💬
48 Pertussis 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
49 Pertussis 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
50 Pertussis 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
51 Pertussis 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
52 Pertussis 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
53 Pertussis 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
54 Pertussis 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
55 Prion disease 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
56 Prion disease 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
57 Prion disease 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
58 Prion disease 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
59 Prion disease 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
60 Prion disease 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
61 Prion disease 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
62 Regulation of actin cytoskeleton 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
63 Regulation of actin cytoskeleton 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
64 Regulation of actin cytoskeleton 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
65 Regulation of actin cytoskeleton 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
66 Regulation of actin cytoskeleton 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
67 Regulation of actin cytoskeleton 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
68 Regulation of actin cytoskeleton 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
69 Staphylococcus aureus infection 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
70 Staphylococcus aureus infection 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
71 Staphylococcus aureus infection 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
72 Staphylococcus aureus infection 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
73 Staphylococcus aureus infection 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
74 Staphylococcus aureus infection 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
75 Staphylococcus aureus infection 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬
76 Staphylococcus aureus infection 💬
[1] C5AR1 💬 Avacopan 💬 Avacopan [3] 43, 44, 222 💬
77 Systemic lupus erythematosus 💬
[1] C5 💬 Crovalimab 💬 Crovalimab [2] 62, 109 💬
78 Systemic lupus erythematosus 💬
[1] C5 💬 Eculizumab 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
79 Systemic lupus erythematosus 💬
[1] C5 💬 Nomacopan 💬 Nomacopan [3] 62, 109, 162 💬
80 Systemic lupus erythematosus 💬
[1] C5 💬 Pozelimab 💬 Pozelimab [2] 11, 62 💬
81 Systemic lupus erythematosus 💬
[1] C5 💬 Ravulizumab 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
82 Systemic lupus erythematosus 💬
[1] C5 💬 Vilobelimab 💬 Vilobelimab [3] 43, 44, 269 💬
83 Systemic lupus erythematosus 💬
[1] C5 💬 Zilucoplan 💬 Zilucoplan [3]  2 , 11, 62 💬