Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Bile secretion 💬
[1] CA2 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
2 Bile secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
3 Bile secretion 💬
[1] CA2 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬
4 Bile secretion 💬
[1] CA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
5 Collecting duct acid secretion 💬
[1] CA2 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
6 Collecting duct acid secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
7 Collecting duct acid secretion 💬
[1] CA2 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬
8 Collecting duct acid secretion 💬
[1] CA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
9 Gastric acid secretion 💬
[1] CA2 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
10 Gastric acid secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
11 Gastric acid secretion 💬
[1] CA2 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬
12 Gastric acid secretion 💬
[1] CA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
13 Metabolic pathways 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
14 Metabolic pathways 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
15 Metabolic pathways 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬
16 Metabolic pathways 💬
[2] CA2, CA4 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
17 Nitrogen metabolism 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
18 Nitrogen metabolism 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
19 Nitrogen metabolism 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬
20 Nitrogen metabolism 💬
[2] CA2, CA4 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
21 Pancreatic secretion 💬
[1] CA2 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
22 Pancreatic secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
23 Pancreatic secretion 💬
[1] CA2 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬
24 Pancreatic secretion 💬
[1] CA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
25 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
26 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬
27 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬
28 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬