Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Allograft rejection 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
2 Allograft rejection 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
3 Allograft rejection 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
4 Allograft rejection 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
5 Asthma 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
6 Asthma 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
7 Asthma 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
8 Asthma 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
9 Autoimmune thyroid disease 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
10 Autoimmune thyroid disease 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
11 Autoimmune thyroid disease 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
12 Autoimmune thyroid disease 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
13 Cell adhesion molecules 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
14 Cell adhesion molecules 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
15 Cell adhesion molecules 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
16 Cell adhesion molecules 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
17 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
18 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
19 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
20 Cytokine-cytokine receptor interaction 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
21 Epstein-Barr virus infection 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
22 Epstein-Barr virus infection 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
23 Epstein-Barr virus infection 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
24 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
25 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
26 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
27 Intestinal immune network for IgA production 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
28 Intestinal immune network for IgA production 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
29 Intestinal immune network for IgA production 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
30 Intestinal immune network for IgA production 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
31 Lipid and atherosclerosis 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
32 Lipid and atherosclerosis 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
33 Lipid and atherosclerosis 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
34 Lipid and atherosclerosis 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
35 Malaria 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
36 Malaria 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
37 Malaria 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
38 Malaria 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
39 NF-kappa B signaling pathway 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
40 NF-kappa B signaling pathway 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
41 NF-kappa B signaling pathway 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
42 NF-kappa B signaling pathway 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
43 Primary immunodeficiency 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
44 Primary immunodeficiency 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
45 Primary immunodeficiency 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
46 Primary immunodeficiency 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
47 Systemic lupus erythematosus 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
48 Systemic lupus erythematosus 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
49 Systemic lupus erythematosus 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
50 Systemic lupus erythematosus 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
51 T cell receptor signaling pathway 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
52 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
53 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
54 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
55 Toxoplasmosis 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
56 Toxoplasmosis 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
57 Toxoplasmosis 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
58 Toxoplasmosis 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬
59 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
60 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
61 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
62 Viral myocarditis 💬
 [1] CD40 💬 Bleselumab 💬 Bleselumab [1] 222 💬
63 Viral myocarditis 💬
 [1] CD40 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
64 Viral myocarditis 💬
 [1] CD40 💬 Ravagalimab 💬 Ravagalimab [2] 53, 97 💬
65 Viral myocarditis 💬
 [1] CD40LG 💬 Toralizumab 💬 Toralizumab [1] 63 💬

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