Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alzheimer disease 💬
 [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
2 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
3 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
4 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
5 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
6 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
7 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
8 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
9 Calcium signaling pathway 💬
 [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
10 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
11 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
12 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
13 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
14 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
15 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
16 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
17 cAMP signaling pathway 💬
 [6] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2 💬 Propiverine 💬 Propiverine [1] 226 💬
18 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Atropine 💬 Atropine [2]  2 , 299 💬
19 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
20 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
21 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Scopolamine 💬 Scopolamine [1]  2  💬
22 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
23 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Tropicamide 💬 Tropicamide [1]  6  💬
24 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
25 Cholinergic synapse 💬
 [9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
26 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
27 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
28 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
29 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
30 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
31 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
32 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
33 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
34 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
35 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
36 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
37 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
38 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
39 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
40 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
41 Pathways of neurodegeneration - multiple diseases 💬
 [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
42 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
43 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
44 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
45 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
46 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
47 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
48 Pathways of neurodegeneration - multiple diseases 💬
 [4] CHRM1, CHRM3, CHRM5, SIGMAR1 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
49 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Atropine 💬 Atropine [2]  2 , 299 💬
50 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
51 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
52 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
53 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Propiverine 💬 Propiverine [1] 226 💬
54 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Scopolamine 💬 Scopolamine [1]  2  💬
55 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
56 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Tropicamide 💬 Tropicamide [1]  6  💬
57 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
58 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
59 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
60 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
61 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
62 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
63 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
64 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬

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