Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alzheimer disease 💬
 [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
2 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
3 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
4 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
5 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
6 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
7 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
8 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
9 Alzheimer disease 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
10 Alzheimer disease 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
11 Alzheimer disease 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
12 Alzheimer disease 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
13 Alzheimer disease 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
14 Alzheimer disease 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
15 Calcium signaling pathway 💬
 [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
16 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
17 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
18 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
19 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
20 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
21 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
22 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
23 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
24 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
25 Calcium signaling pathway 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
26 Calcium signaling pathway 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
27 Calcium signaling pathway 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
28 Calcium signaling pathway 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
29 Cholinergic synapse 💬
 [9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
30 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
31 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
32 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
33 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
34 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
35 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
36 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
37 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
38 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
39 Cholinergic synapse 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
40 Cholinergic synapse 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
41 Cholinergic synapse 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
42 Cholinergic synapse 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
43 Gastric acid secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
44 Gastric acid secretion 💬
 [1] CHRM3 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
45 Gastric acid secretion 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
46 Gastric acid secretion 💬
 [1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
47 Gastric acid secretion 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
48 Gastric acid secretion 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
49 Gastric acid secretion 💬
 [1] CHRM3 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
50 Gastric acid secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
51 Gastric acid secretion 💬
 [1] CHRM3 💬 Propiverine 💬 Propiverine [1] 226 💬
52 Gastric acid secretion 💬
 [1] CHRM3 💬 Scopolamine 💬 Scopolamine [1]  2  💬
53 Gastric acid secretion 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
54 Gastric acid secretion 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
55 Gastric acid secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
56 Gastric acid secretion 💬
 [1] CHRM3 💬 Tropicamide 💬 Tropicamide [1]  6  💬
57 Insulin secretion 💬
 [5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM3 💬 Propiverine 💬 Propiverine [1] 226 💬
58 Insulin secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
59 Insulin secretion 💬
 [1] CHRM3 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
60 Insulin secretion 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
61 Insulin secretion 💬
 [1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
62 Insulin secretion 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
63 Insulin secretion 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
64 Insulin secretion 💬
 [1] CHRM3 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
65 Insulin secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
66 Insulin secretion 💬
 [1] CHRM3 💬 Scopolamine 💬 Scopolamine [1]  2  💬
67 Insulin secretion 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
68 Insulin secretion 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
69 Insulin secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
70 Insulin secretion 💬
 [1] CHRM3 💬 Tropicamide 💬 Tropicamide [1]  6  💬
71 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
72 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
73 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
74 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
75 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
76 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
77 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
78 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
79 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
80 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
81 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
82 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
83 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
84 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
85 Pancreatic secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
86 Pancreatic secretion 💬
 [1] CHRM3 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
87 Pancreatic secretion 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
88 Pancreatic secretion 💬
 [1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
89 Pancreatic secretion 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
90 Pancreatic secretion 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
91 Pancreatic secretion 💬
 [1] CHRM3 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
92 Pancreatic secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
93 Pancreatic secretion 💬
 [1] CHRM3 💬 Propiverine 💬 Propiverine [1] 226 💬
94 Pancreatic secretion 💬
 [1] CHRM3 💬 Scopolamine 💬 Scopolamine [1]  2  💬
95 Pancreatic secretion 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
96 Pancreatic secretion 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
97 Pancreatic secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
98 Pancreatic secretion 💬
 [1] CHRM3 💬 Tropicamide 💬 Tropicamide [1]  6  💬
99 Pathways of neurodegeneration - multiple diseases 💬
 [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM3, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
100 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
101 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
102 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
103 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
104 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
105 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
106 Pathways of neurodegeneration - multiple diseases 💬
 [4] CHRM1, CHRM3, CHRM5, SIGMAR1 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
107 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
108 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
109 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
110 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
111 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
112 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
113 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
114 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
115 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
116 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
117 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine [1] 226 💬
118 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine [1]  2  💬
119 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
120 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide [1]  6  💬
121 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
122 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
123 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
124 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
125 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
126 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
127 Salivary secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
128 Salivary secretion 💬
 [1] CHRM3 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
129 Salivary secretion 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
130 Salivary secretion 💬
 [1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
131 Salivary secretion 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
132 Salivary secretion 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
133 Salivary secretion 💬
 [1] CHRM3 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
134 Salivary secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
135 Salivary secretion 💬
 [1] CHRM3 💬 Propiverine 💬 Propiverine [1] 226 💬
136 Salivary secretion 💬
 [1] CHRM3 💬 Scopolamine 💬 Scopolamine [1]  2  💬
137 Salivary secretion 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
138 Salivary secretion 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
139 Salivary secretion 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
140 Salivary secretion 💬
 [1] CHRM3 💬 Tropicamide 💬 Tropicamide [1]  6  💬
141 Taste transduction 💬
 [2] CACNA1C, CHRM3 💬 Propiverine 💬 Propiverine [1] 226 💬
142 Taste transduction 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
143 Taste transduction 💬
 [1] CHRM3 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬
144 Taste transduction 💬
 [1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬
145 Taste transduction 💬
 [1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
146 Taste transduction 💬
 [1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬
147 Taste transduction 💬
 [1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬
148 Taste transduction 💬
 [1] CHRM3 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬
149 Taste transduction 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
150 Taste transduction 💬
 [1] CHRM3 💬 Scopolamine 💬 Scopolamine [1]  2  💬
151 Taste transduction 💬
 [1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬
152 Taste transduction 💬
 [1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬
153 Taste transduction 💬
 [1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬
154 Taste transduction 💬
 [1] CHRM3 💬 Tropicamide 💬 Tropicamide [1]  6  💬

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