Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬
2 Alcoholism 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
3 Alcoholism 💬
[2] DRD1, DRD2 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
4 Alcoholism 💬
[2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
5 Alcoholism 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
6 Alcoholism 💬
[2] DRD1, DRD2 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
7 Alcoholism 💬
[2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
8 Alcoholism 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
9 Amphetamine addiction 💬
[1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
10 Amphetamine addiction 💬
[1] DRD1 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
11 Amphetamine addiction 💬
[1] DRD1 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
12 Amphetamine addiction 💬
[1] DRD1 💬 Flupentixol 💬 Flupentixol [1] 97 💬
13 Amphetamine addiction 💬
[1] DRD1 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
14 Amphetamine addiction 💬
[1] DRD1 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
15 Amphetamine addiction 💬
[1] DRD1 💬 Pergolide 💬 Pergolide [1]  6  💬
16 Amphetamine addiction 💬
[1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬
17 Calcium signaling pathway 💬
[1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
18 Calcium signaling pathway 💬
[1] DRD1 💬 Flupentixol 💬 Flupentixol [1] 97 💬
19 Calcium signaling pathway 💬
[1] DRD1 💬 Pergolide 💬 Pergolide [1]  6  💬
20 Calcium signaling pathway 💬
[2] DRD1, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
21 Calcium signaling pathway 💬
[2] DRD1, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
22 Calcium signaling pathway 💬
[2] DRD1, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
23 Calcium signaling pathway 💬
[2] DRD1, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
24 Calcium signaling pathway 💬
[2] DRD1, DRD5 💬 Tavapadon 💬 Tavapadon [1]  6  💬
25 cAMP signaling pathway 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
26 cAMP signaling pathway 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
27 cAMP signaling pathway 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
28 cAMP signaling pathway 💬
[3] DRD1, DRD2, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
29 cAMP signaling pathway 💬
[3] DRD1, DRD2, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
30 cAMP signaling pathway 💬
[3] DRD1, DRD2, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
31 cAMP signaling pathway 💬
[3] DRD1, DRD2, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
32 cAMP signaling pathway 💬
[2] DRD1, DRD5 💬 Tavapadon 💬 Tavapadon [1]  6  💬
33 Cocaine addiction 💬
[1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬
34 Cocaine addiction 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
35 Cocaine addiction 💬
[2] DRD1, DRD2 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
36 Cocaine addiction 💬
[2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
37 Cocaine addiction 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
38 Cocaine addiction 💬
[2] DRD1, DRD2 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
39 Cocaine addiction 💬
[2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
40 Cocaine addiction 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
41 Dopaminergic synapse 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
42 Dopaminergic synapse 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
43 Dopaminergic synapse 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
44 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
45 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
46 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
47 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
48 Dopaminergic synapse 💬
[2] DRD1, DRD5 💬 Tavapadon 💬 Tavapadon [1]  6  💬
49 Gap junction 💬
[1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬
50 Gap junction 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
51 Gap junction 💬
[2] DRD1, DRD2 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
52 Gap junction 💬
[2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
53 Gap junction 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
54 Gap junction 💬
[2] DRD1, DRD2 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
55 Gap junction 💬
[2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
56 Gap junction 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
57 Morphine addiction 💬
[1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
58 Morphine addiction 💬
[1] DRD1 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
59 Morphine addiction 💬
[1] DRD1 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
60 Morphine addiction 💬
[1] DRD1 💬 Flupentixol 💬 Flupentixol [1] 97 💬
61 Morphine addiction 💬
[1] DRD1 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
62 Morphine addiction 💬
[1] DRD1 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
63 Morphine addiction 💬
[1] DRD1 💬 Pergolide 💬 Pergolide [1]  6  💬
64 Morphine addiction 💬
[1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬
65 Neuroactive ligand-receptor interaction 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
66 Neuroactive ligand-receptor interaction 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
67 Neuroactive ligand-receptor interaction 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬
68 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
69 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
70 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
71 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
72 Neuroactive ligand-receptor interaction 💬
[2] DRD1, DRD5 💬 Tavapadon 💬 Tavapadon [1]  6  💬
73 Parkinson disease 💬
[1] DRD1 💬 Tavapadon 💬 Tavapadon [1]  6  💬
74 Parkinson disease 💬
[2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
75 Parkinson disease 💬
[2] DRD1, DRD2 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
76 Parkinson disease 💬
[2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
77 Parkinson disease 💬
[2] DRD1, DRD2 💬 Flupentixol 💬 Flupentixol [1] 97 💬
78 Parkinson disease 💬
[2] DRD1, DRD2 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
79 Parkinson disease 💬
[2] DRD1, DRD2 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
80 Parkinson disease 💬
[2] DRD1, DRD2 💬 Pergolide 💬 Pergolide [1]  6  💬