Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
2 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
3 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
4 Dopaminergic synapse 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
5 Dopaminergic synapse 💬
[2] DRD2, DRD3 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
6 Dopaminergic synapse 💬
[2] DRD2, DRD3 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
7 Dopaminergic synapse 💬
[2] DRD2, DRD3 💬 Piribedil 💬 Piribedil [1]  6  💬
8 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Lisuride 💬 Lisuride [2]  6 , 86 💬
9 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
10 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Pramipexole 💬 Pramipexole [3]  2 ,  6 , 20 💬
11 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 Ropinirole 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
12 Neuroactive ligand-receptor interaction 💬
[11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
13 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dexpramipexole 💬 Dexpramipexole [1]  2  💬
14 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
15 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Foslevodopa 💬 Foslevodopa [1]  6  💬
16 Neuroactive ligand-receptor interaction 💬
[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Levodopa 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
17 Neuroactive ligand-receptor interaction 💬
[2] DRD2, DRD3 💬 Piribedil 💬 Piribedil [1]  6  💬
18 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, DRD4 💬 Lisuride 💬 Lisuride [2]  6 , 86 💬
19 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, DRD4 💬 Pramipexole 💬 Pramipexole [3]  2 ,  6 , 20 💬
20 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, DRD4 💬 Ropinirole 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
21 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, HTR1A 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
22 Neuroactive ligand-receptor interaction 💬
[4] DRD2, DRD3, HTR1A, HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬