Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
2 Calcium signaling pathway 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
3 Calcium signaling pathway 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
4 Calcium signaling pathway 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
5 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
6 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
7 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
8 cAMP signaling pathway 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
9 cAMP signaling pathway 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
10 cAMP signaling pathway 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
11 cAMP signaling pathway 💬
 [1] EDNRA 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
12 cAMP signaling pathway 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
13 cAMP signaling pathway 💬
 [1] EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
14 cAMP signaling pathway 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
15 cGMP-PKG signaling pathway 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
16 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
17 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
18 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
19 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
20 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
21 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
22 Neuroactive ligand-receptor interaction 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
23 Neuroactive ligand-receptor interaction 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
24 Neuroactive ligand-receptor interaction 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
25 Neuroactive ligand-receptor interaction 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
26 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
27 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
28 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
29 Pathways in cancer 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
30 Pathways in cancer 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
31 Pathways in cancer 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
32 Pathways in cancer 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
33 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
34 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
35 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
36 Renin secretion 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
37 Renin secretion 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
38 Renin secretion 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
39 Renin secretion 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
40 Renin secretion 💬
 [1] EDNRA 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
41 Renin secretion 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
42 Renin secretion 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬
43 Vascular smooth muscle contraction 💬
 [2] AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
44 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Ambrisentan 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
45 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
46 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
47 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
48 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Sitaxentan 💬 Sitaxentan [1] 86 💬
49 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 Zibotentan 💬 Zibotentan [1] 51 💬

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