Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
2 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
3 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
4 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
5 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
6 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
7 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
8 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
9 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
10 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
11 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
12 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
13 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [3] AR, ESR1, ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
14 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
15 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
16 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
17 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
18 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
19 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
20 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
21 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
22 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
23 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
24 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
25 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
26 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
27 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
28 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
29 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
30 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
31 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
32 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
33 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
34 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
35 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
36 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
37 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
38 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
39 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
40 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
41 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
42 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
43 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
44 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
45 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
46 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
47 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
48 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
49 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
50 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
51 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
52 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
53 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
54 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
55 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
56 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
57 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
58 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
59 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
60 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
ESR2 [1] ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
61 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [3] AR, ESR1, ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
62 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
63 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
64 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
65 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
66 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
67 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
68 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
69 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
70 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
71 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
72 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|
73 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Clomifene Clomifene 💬
| Clomifene | 074 [1] 74 💬
|
74 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
75 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estetrol Estetrol 💬
| Estetrol | 053 [1] 53 💬
|
76 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol Estradiol 💬
| Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
|
77 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estradiol valerate Estradiol valerate 💬
| Estradiol valerate | 065 [1] 65 💬
|
78 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol Estriol 💬
| Estriol | 013 [2] 13, 227 💬
|
79 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Estriol tripropionate Estriol tripropionate 💬
| Estriol | 013 [2] 13, 227 💬
|
80 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Fulvestrant Fulvestrant 💬
| Fulvestrant | 049 [2] 49, 86 💬
|
81 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Mestranol Mestranol 💬
| Mestranol | 046 [2] 46, 49 💬
|
82 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Prasterone Prasterone 💬
| Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
|
83 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Raloxifene Raloxifene 💬
| Raloxifene | 046 [1] 46 💬
|
84 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 [2] ESR1, ESR2 💬
|
Tamoxifen Tamoxifen 💬
| Tamoxifen | 002 [3] 2 , 113, 227 💬
|