Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 cAMP signaling pathway 💬
[2] DRD2, HTR1A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
2 cAMP signaling pathway 💬
[2] DRD2, HTR1A 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬
3 cAMP signaling pathway 💬
[2] DRD2, HTR1A 💬 Cariprazine 💬 Cariprazine [1] 21 💬
4 cAMP signaling pathway 💬
[2] DRD2, HTR1A 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
5 cAMP signaling pathway 💬
[1] HTR1A 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬
6 Neuroactive ligand-receptor interaction 💬
[3] DRD2, DRD3, HTR1A 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
7 Neuroactive ligand-receptor interaction 💬
[4] DRD2, DRD3, HTR1A, HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
8 Neuroactive ligand-receptor interaction 💬
[2] DRD2, HTR1A 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬
9 Neuroactive ligand-receptor interaction 💬
[3] DRD2, HTR1A, HTR2A 💬 Cariprazine 💬 Cariprazine [1] 21 💬
10 Neuroactive ligand-receptor interaction 💬
[1] HTR1A 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬
11 Serotonergic synapse 💬
[1] HTR1A 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬
12 Serotonergic synapse 💬
[1] HTR1A 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
13 Serotonergic synapse 💬
[2] HTR1A, HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
14 Serotonergic synapse 💬
[2] HTR1A, HTR2A 💬 Cariprazine 💬 Cariprazine [1] 21 💬
15 Serotonergic synapse 💬
[7] HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E, SLC6A4 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬
16 Taste transduction 💬
[1] HTR1A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
17 Taste transduction 💬
[1] HTR1A 💬 Buspirone 💬 Buspirone [2]  6 , 51 💬
18 Taste transduction 💬
[1] HTR1A 💬 Cariprazine 💬 Cariprazine [1] 21 💬
19 Taste transduction 💬
[1] HTR1A 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
20 Taste transduction 💬
[6] HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬