Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
[8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
2 Calcium signaling pathway 💬
[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
3 Calcium signaling pathway 💬
[3] HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
4 Calcium signaling pathway 💬
[3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
5 Gap junction 💬
[4] DRD2, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
6 Gap junction 💬
[4] DRD2, HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
7 Gap junction 💬
[4] DRD2, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
8 Gap junction 💬
[3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
9 Inflammatory mediator regulation of TRP channels 💬
[4] HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
10 Inflammatory mediator regulation of TRP channels 💬
[4] HRH1, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
11 Inflammatory mediator regulation of TRP channels 💬
[3] HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
12 Inflammatory mediator regulation of TRP channels 💬
[3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
13 Neuroactive ligand-receptor interaction 💬
[11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
14 Neuroactive ligand-receptor interaction 💬
[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
15 Neuroactive ligand-receptor interaction 💬
[4] DRD2, HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
16 Neuroactive ligand-receptor interaction 💬
[3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
17 Serotonergic synapse 💬
[3] HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
18 Serotonergic synapse 💬
[3] HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
19 Serotonergic synapse 💬
[4] HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
20 Serotonergic synapse 💬
[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬 Trazodone 💬 Trazodone [1]  2  💬