Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 2 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 3 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 4 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 5 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 6 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 7 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 8 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 9 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 10 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 11 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 12 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 13 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 14 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 15 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 16 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 17 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 18 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 19 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 20 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 21 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 22 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 23 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 24 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 25 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 26 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 27 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 28 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 29 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 30 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 31 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 32 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 33 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 34 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 35 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 36 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 37 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 38 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 39 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 40 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 41 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 42 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 43 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 44 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 45 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 46 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 47 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 48 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 49 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 50 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 51 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 52 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 53 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 54 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 55 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 56 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 57 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 58 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 59 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 60 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 61 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 62 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 63 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 64 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR [2] GHR, IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 65 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 66 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 67 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 68 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 69 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 70 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 71 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 72 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 73 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 74 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 75 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 76 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 77 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 78 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 79 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 80 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 81 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 82 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 83 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 84 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|
| 85 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IGF1R [1] IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 [1] 232 💬
|
| 86 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IGF1R [1] IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬
|
| 87 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IGF1R [1] IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 [1] 51 💬
|