Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 cAMP signaling pathway 💬
[8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Aminophylline 💬 Aminophylline [1] 63 💬
2 cAMP signaling pathway 💬
[8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
3 cAMP signaling pathway 💬
[8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
4 cAMP signaling pathway 💬
[7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Bucladesine 💬 Bucladesine [1] 246 💬
5 cAMP signaling pathway 💬
[7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Flavoxate 💬 Flavoxate [1] 226 💬
6 Metabolic pathways 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
7 Metabolic pathways 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
8 Metabolic pathways 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
9 Metabolic pathways 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
10 Metabolic pathways 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
11 Morphine addiction 💬
[17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
12 Morphine addiction 💬
[17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
13 Morphine addiction 💬
[17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
14 Morphine addiction 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
15 Morphine addiction 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
16 Purine metabolism 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
17 Purine metabolism 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
18 Purine metabolism 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
19 Purine metabolism 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
20 Purine metabolism 💬
[16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬