Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 AMPK signaling pathway 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
2 AMPK signaling pathway 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
3 AMPK signaling pathway 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
4 AMPK signaling pathway 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
5 AMPK signaling pathway 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
6 Huntington disease 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
7 Huntington disease 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
8 Huntington disease 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
9 Huntington disease 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
10 Huntington disease 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
11 Lipid and atherosclerosis 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
12 Lipid and atherosclerosis 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
13 Lipid and atherosclerosis 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
14 Lipid and atherosclerosis 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
15 Lipid and atherosclerosis 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
16 Longevity regulating pathway 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
17 Longevity regulating pathway 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
18 Longevity regulating pathway 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
19 Longevity regulating pathway 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
20 Longevity regulating pathway 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
21 Non-alcoholic fatty liver disease 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
22 Non-alcoholic fatty liver disease 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
23 Non-alcoholic fatty liver disease 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
24 Non-alcoholic fatty liver disease 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
25 Non-alcoholic fatty liver disease 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
26 Osteoclast differentiation 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
27 Osteoclast differentiation 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
28 Osteoclast differentiation 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
29 Osteoclast differentiation 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
30 Osteoclast differentiation 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
31 Pathways in cancer 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
32 Pathways in cancer 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
33 Pathways in cancer 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
34 Pathways in cancer 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
35 Pathways in cancer 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
36 PPAR signaling pathway 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
37 PPAR signaling pathway 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
38 PPAR signaling pathway 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
39 PPAR signaling pathway 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
40 PPAR signaling pathway 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
41 Thermogenesis 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
42 Thermogenesis 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
43 Thermogenesis 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
44 Thermogenesis 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
45 Thermogenesis 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
46 Thyroid cancer 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
47 Thyroid cancer 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
48 Thyroid cancer 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
49 Thyroid cancer 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
50 Thyroid cancer 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬
51 Transcriptional misregulation in cancer 💬
[1] PPARG 💬 Bocidelpar 💬 Bocidelpar [1] 113 💬
52 Transcriptional misregulation in cancer 💬
[1] PPARG 💬 Leriglitazone 💬 Leriglitazone [1] 20 💬
53 Transcriptional misregulation in cancer 💬
[1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
54 Transcriptional misregulation in cancer 💬
[1] PPARG 💬 Rosiglitazone 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
55 Transcriptional misregulation in cancer 💬
[1] PPARG 💬 Seladelpar 💬 Seladelpar [2] 93, 94 💬