Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alzheimer disease 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
2 Alzheimer disease 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
3 Alzheimer disease 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
4 Amyotrophic lateral sclerosis 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
5 Amyotrophic lateral sclerosis 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
6 Amyotrophic lateral sclerosis 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
7 Huntington disease 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
8 Huntington disease 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
9 Huntington disease 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
10 Parkinson disease 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
11 Parkinson disease 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
12 Parkinson disease 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
13 Pathways of neurodegeneration - multiple diseases 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
14 Pathways of neurodegeneration - multiple diseases 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
15 Pathways of neurodegeneration - multiple diseases 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
16 Prion disease 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
17 Prion disease 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
18 Prion disease 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
19 Proteasome 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
20 Proteasome 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
21 Proteasome 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
22 Spinocerebellar ataxia 💬
[1] PSMB5 💬 Bortezomib 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
23 Spinocerebellar ataxia 💬
[1] PSMB5 💬 Carfilzomib 💬 Carfilzomib [1] 28 💬
24 Spinocerebellar ataxia 💬
[1] PSMB5 💬 Ixazomib 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬