Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
2 Adipocytokine signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
3 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
4 Alcoholic liver disease 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
5 Alzheimer disease 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
6 Amoebiasis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
7 Antifolate resistance 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
8 Apoptosis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
9 B cell receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
10 C-type lectin receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
11 cAMP signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
12 Cellular senescence 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
13 Chagas disease 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
14 Chemical carcinogenesis - reactive oxygen species 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
15 Chemical carcinogenesis - receptor activation 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
16 Chemokine signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
17 Chronic myeloid leukemia 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
18 Cocaine addiction 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
19 Coronavirus disease - COVID-19 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
20 Cytosolic DNA-sensing pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
21 Diabetic cardiomyopathy 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
22 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
23 Epstein-Barr virus infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
24 Fluid shear stress and atherosclerosis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
25 Hepatitis B 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
26 Hepatitis C 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
27 Herpes simplex virus 1 infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
28 HIF-1 signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
29 Human cytomegalovirus infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
30 Human immunodeficiency virus 1 infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
31 Human papillomavirus infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
32 Human T-cell leukemia virus 1 infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
33 IL-17 signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
34 Inflammatory bowel disease 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
35 Influenza A 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
36 Insulin resistance 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
37 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
38 Legionellosis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
39 Leishmaniasis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
40 Lipid and atherosclerosis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
41 Longevity regulating pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
42 MAPK signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
43 Measles 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
44 Mitophagy - animal 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
45 Neurotrophin signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
46 Neutrophil extracellular trap formation 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
47 NF-kappa B signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
48 NOD-like receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
49 Non-alcoholic fatty liver disease 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
50 Osteoclast differentiation 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
51 Pancreatic cancer 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
52 Pathogenic Escherichia coli infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
53 Pathways in cancer 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
54 Pathways of neurodegeneration - multiple diseases 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
55 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
56 Pertussis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
57 PI3K-Akt signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
58 Prolactin signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
59 Prostate cancer 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
60 Ras signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
61 Relaxin signaling pathway 💬
 [1] EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
62 Relaxin signaling pathway 💬
 [1] EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
63 Relaxin signaling pathway 💬
 [1] EDNRB 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
64 Relaxin signaling pathway 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬
65 Relaxin signaling pathway 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬
66 Relaxin signaling pathway 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
67 Relaxin signaling pathway 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
68 Relaxin signaling pathway 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
69 Relaxin signaling pathway 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
70 Relaxin signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
71 Relaxin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
72 Relaxin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
73 Relaxin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
74 Relaxin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
75 Relaxin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
76 Relaxin signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
77 Relaxin signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
78 Relaxin signaling pathway 💬
 [1] MMP13 💬 Apratastat 💬 Apratastat [1] 46 💬
79 Relaxin signaling pathway 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
80 Relaxin signaling pathway 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
81 Relaxin signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
82 Relaxin signaling pathway 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
83 Relaxin signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
84 Relaxin signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
85 Relaxin signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
86 Relaxin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
87 Relaxin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
88 Relaxin signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
89 Relaxin signaling pathway 💬
 [1] TGFB1 💬 Fresolimumab 💬 Fresolimumab [3] 51, 85, 222 💬
90 Relaxin signaling pathway 💬
 [1] VEGFA 💬 Bevacizumab 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
91 Relaxin signaling pathway 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
92 Relaxin signaling pathway 💬
 [2] VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
93 RIG-I-like receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
94 Salmonella infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
95 Shigellosis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
96 Small cell lung cancer 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
97 Sphingolipid signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
98 T cell receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
99 Th1 and Th2 cell differentiation 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
100 Th17 cell differentiation 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
101 TNF signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
102 Toll-like receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
103 Toxoplasmosis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
104 Transcriptional misregulation in cancer 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
105 Tuberculosis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
106 Viral carcinogenesis 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
107 Yersinia infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬

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