Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Drug metabolism - other enzymes 💬

[1] RRM1 💬

Cladribine 💬

Cladribine

[3] 11, 13, 94 💬

Drug metabolism - other enzymes 💬

[1] RRM1 💬

Clofarabine 💬

Clofarabine

[5] 19, 20, 60, 234, 326 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
60	Aplastic anemia;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
326	Osteopetrosis;

Drug metabolism - other enzymes 💬

[1] RRM1 💬

Fludarabine 💬

Fludarabine

[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
28	Systemic amyloidosis;AL amyloidosis;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
164	Oculocutaneous albinism;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
326	Osteopetrosis;

Glutathione metabolism 💬

[1] RRM1 💬

Cladribine 💬

Cladribine

[3] 11, 13, 94 💬

Glutathione metabolism 💬

[1] RRM1 💬

Clofarabine 💬

Clofarabine

[5] 19, 20, 60, 234, 326 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
60	Aplastic anemia;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
326	Osteopetrosis;

Glutathione metabolism 💬

[1] RRM1 💬

Fludarabine 💬

Fludarabine

[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
28	Systemic amyloidosis;AL amyloidosis;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
164	Oculocutaneous albinism;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
326	Osteopetrosis;

Metabolic pathways 💬

[1] RRM1 💬

Cladribine 💬

Cladribine

[3] 11, 13, 94 💬

Metabolic pathways 💬

[1] RRM1 💬

Clofarabine 💬

Clofarabine

[5] 19, 20, 60, 234, 326 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
60	Aplastic anemia;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
326	Osteopetrosis;

Metabolic pathways 💬

[1] RRM1 💬

Fludarabine 💬

Fludarabine

[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
28	Systemic amyloidosis;AL amyloidosis;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
164	Oculocutaneous albinism;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
326	Osteopetrosis;

Nucleotide metabolism 💬

[1] RRM1 💬

Cladribine 💬

Cladribine

[3] 11, 13, 94 💬

Nucleotide metabolism 💬

[1] RRM1 💬

Clofarabine 💬

Clofarabine

[5] 19, 20, 60, 234, 326 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
60	Aplastic anemia;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
326	Osteopetrosis;

Nucleotide metabolism 💬

[1] RRM1 💬

Fludarabine 💬

Fludarabine

[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
28	Systemic amyloidosis;AL amyloidosis;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
164	Oculocutaneous albinism;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
326	Osteopetrosis;

Purine metabolism 💬

[1] RRM1 💬

Cladribine 💬

Cladribine

[3] 11, 13, 94 💬

Purine metabolism 💬

[1] RRM1 💬

Clofarabine 💬

Clofarabine

[5] 19, 20, 60, 234, 326 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
60	Aplastic anemia;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
326	Osteopetrosis;

Purine metabolism 💬

[1] RRM1 💬

Fludarabine 💬

Fludarabine

[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
28	Systemic amyloidosis;AL amyloidosis;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
164	Oculocutaneous albinism;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
326	Osteopetrosis;

Pyrimidine metabolism 💬

[1] RRM1 💬

Cladribine 💬

Cladribine

[3] 11, 13, 94 💬

Pyrimidine metabolism 💬

[1] RRM1 💬

Clofarabine 💬

Clofarabine

[5] 19, 20, 60, 234, 326 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
60	Aplastic anemia;
234	Peroxisomal disease (except Adrenoleukodystrophy);Peroxisomal disease;Peroxisomal disorder;Peroxisome biogenesis disorder;
326	Osteopetrosis;

Pyrimidine metabolism 💬

[1] RRM1 💬

Fludarabine 💬

Fludarabine

[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
28	Systemic amyloidosis;AL amyloidosis;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
60	Aplastic anemia;
61	Autoimmune hemolytic anemia;AIHA;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
65	Primary immunodeficiency;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
164	Oculocutaneous albinism;
283	Acquired pure red cell aplasia;Pure red cell aplasia;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
286	Hereditary sideroblastic anemia;Congenital sideroblastic anemia;Sideroblastic anemia;
326	Osteopetrosis;