Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adipocytokine signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
2 Adipocytokine signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
3 Adipocytokine signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
4 Bile secretion 💬
 [1] RXRA 💬 Acitretin 💬 Acitretin [1] 37 💬
5 Bile secretion 💬
 [1] RXRA 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
6 Bile secretion 💬
 [1] RXRA 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
7 Chemical carcinogenesis - receptor activation 💬
 [3] RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
8 Chemical carcinogenesis - receptor activation 💬
 [3] RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
9 Chemical carcinogenesis - receptor activation 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
10 Gastric cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
11 Gastric cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
12 Gastric cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
13 Hepatitis C 💬
 [1] RXRA 💬 Acitretin 💬 Acitretin [1] 37 💬
14 Hepatitis C 💬
 [1] RXRA 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
15 Hepatitis C 💬
 [1] RXRA 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
16 Lipid and atherosclerosis 💬
 [3] RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
17 Lipid and atherosclerosis 💬
 [3] RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
18 Lipid and atherosclerosis 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
19 Non-alcoholic fatty liver disease 💬
 [1] RXRA 💬 Acitretin 💬 Acitretin [1] 37 💬
20 Non-alcoholic fatty liver disease 💬
 [1] RXRA 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
21 Non-alcoholic fatty liver disease 💬
 [1] RXRA 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
22 Non-small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
23 Non-small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
24 Non-small cell lung cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
25 Parathyroid hormone synthesis, secretion and action 💬
 [3] RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
26 Parathyroid hormone synthesis, secretion and action 💬
 [3] RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
27 Parathyroid hormone synthesis, secretion and action 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
28 Pathways in cancer 💬
 [5] RARA, RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
29 Pathways in cancer 💬
 [5] RARA, RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
30 Pathways in cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
31 PI3K-Akt signaling pathway 💬
 [1] RXRA 💬 Acitretin 💬 Acitretin [1] 37 💬
32 PI3K-Akt signaling pathway 💬
 [1] RXRA 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
33 PI3K-Akt signaling pathway 💬
 [1] RXRA 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
34 PPAR signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
35 PPAR signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
36 PPAR signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
37 Small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
38 Small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
39 Small cell lung cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
40 Th17 cell differentiation 💬
 [4] RARA, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
41 Th17 cell differentiation 💬
 [4] RARA, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
42 Th17 cell differentiation 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
43 Thyroid cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
44 Thyroid cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
45 Thyroid cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
46 Thyroid hormone signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
47 Thyroid hormone signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
48 Thyroid hormone signaling pathway 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬
49 Transcriptional misregulation in cancer 💬
 [4] RARA, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬
50 Transcriptional misregulation in cancer 💬
 [4] RARA, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬
51 Transcriptional misregulation in cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬

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