Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Chemokine signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 Chemokine signaling pathway 💬
 [2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
3 Chemokine signaling pathway 💬
 [1] CCL2 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
4 Chemokine signaling pathway 💬
 [2] CCR2, CCR5 💬 Cenicriviroc 💬 Cenicriviroc [1] 94 💬
5 Chemokine signaling pathway 💬
 [1] CCR4 💬 Mogamulizumab 💬 Mogamulizumab [1] 26 💬
6 Chemokine signaling pathway 💬
 [1] CCR5 💬 Maraviroc 💬 Maraviroc [2] 46, 84 💬
7 Chemokine signaling pathway 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
8 Chemokine signaling pathway 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
9 Chemokine signaling pathway 💬
 [1] JAK2 💬 Baricitinib 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
10 Chemokine signaling pathway 💬
 [1] JAK2 💬 Ruxolitinib 💬 Ruxolitinib [3] 60, 65, 228 💬
11 Chemokine signaling pathway 💬
 [2] JAK2, JAK3 💬 Peficitinib 💬 Peficitinib [1] 46 💬
12 Chemokine signaling pathway 💬
 [2] JAK2, JAK3 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
13 Chemokine signaling pathway 💬
 [1] MAP2K1 💬 Binimetinib 💬 Binimetinib [1] 34 💬
14 Chemokine signaling pathway 💬
 [1] MAP2K1 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
15 Chemokine signaling pathway 💬
 [1] MAP2K1 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
16 Chemokine signaling pathway 💬
 [1] MAP2K1 💬 Selumetinib 💬 Selumetinib [1] 34 💬
17 Chemokine signaling pathway 💬
 [1] MAP2K1 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
18 Chemokine signaling pathway 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
19 Chemokine signaling pathway 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
20 Chemokine signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
21 Chemokine signaling pathway 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
22 Chemokine signaling pathway 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
23 Chemokine signaling pathway 💬
 [1] PRKCD 💬 Sotrastaurin 💬 Sotrastaurin [1] 97 💬
24 Chemokine signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
25 Chemokine signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
26 Chemokine signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
27 Chemokine signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
28 Chemokine signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
29 Chemokine signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
30 Chemokine signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬