Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Synaptic vesicle cycle 💬
 [1] CACNA1B 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
2 Synaptic vesicle cycle 💬
 [1] SLC18A2 💬 Deutetrabenazine 💬 Deutetrabenazine [1]  8  💬
3 Synaptic vesicle cycle 💬
 [1] SLC18A2 💬 Tetrabenazine 💬 Tetrabenazine [1]  8  💬
4 Synaptic vesicle cycle 💬
 [1] SLC18A2 💬 Valbenazine 💬 Valbenazine [1]  8  💬
5 Synaptic vesicle cycle 💬
 [1] SLC6A1 💬 Gabapentin 💬 Gabapentin [5]  6 , 13, 19, 70, 298 💬
6 Synaptic vesicle cycle 💬
 [1] SLC6A2 💬 Atomoxetine 💬 Atomoxetine [4]  6 ,  8 , 13, 17 💬
7 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A3 💬 Bupropion 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
8 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
9 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
10 Synaptic vesicle cycle 💬
 [3] SLC6A2, SLC6A3, SLC6A4 💬 Phentermine 💬 Phentermine [1] 97 💬
11 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Amitriptyline 💬 Amitriptyline [4] 78, 97, 226, 299 💬
12 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Amoxapine 💬 Amoxapine [1] 46 💬
13 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Ampreloxetine 💬 Ampreloxetine [2]  6 , 17 💬
14 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Desipramine 💬 Desipramine [2] 120, 156 💬
15 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Doxepin 💬 Doxepin [1]  6  💬
16 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Duloxetine 💬 Duloxetine [2]  6 , 13 💬
17 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Milnacipran 💬 Milnacipran [2] 46, 49 💬
18 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Nortriptyline 💬 Nortriptyline [2]  6 , 226 💬
19 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Venlafaxine 💬 Venlafaxine [3]  6 , 13, 46 💬
20 Synaptic vesicle cycle 💬
 [1] SLC6A3 💬 Armodafinil 💬 Armodafinil [3]  6 , 13, 84 💬
21 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Citalopram 💬 Citalopram [7]  6 ,  8 , 13, 18, 46, 98, 127 💬
22 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Escitalopram 💬 Escitalopram [4]  2 ,  6 , 13, 46 💬
23 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
24 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
25 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Paroxetine 💬 Paroxetine [4]  6 , 13, 46, 85 💬
26 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Sertraline 💬 Sertraline [2]  6 , 206 💬
27 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Trazodone 💬 Trazodone [1]  2  💬
28 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬
29 Synaptic vesicle cycle 💬
 [1] SNAP25 💬 Botulinum toxin type A 💬 Botulinum toxin type A [14]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
30 Synaptic vesicle cycle 💬
 [1] SNAP25 💬 Rimabotulinumtoxin B 💬 Botulinum toxin type B [4]  2 ,  6 , 13, 51 💬